Literature DB >> 6785044

Mutants partially defective in excision repair at five autosomal loci in Drosophila melanogaster.

J B Boyd, P V Harris.   

Abstract

Primary cell cultures derived from mutants in seventeen different genes were analyzed for their ability to excise pyrimidine dimers from DNA. Five of these mutagen-sensitive mutants [mus(2)205A1, mus(3)302D1, mus(3)304D3, mus(3)306D1, mus(3)308D2] display a significantly reduced excision capacity relative to control cultured. In addition, two of the five [mus(3)306D2, mus(3)308D2] are defective in the accumulation of single-strand breaks normally seen after ultraviolet irradiation. This study, therefore, brings the total number of Drosophila mutants known to be defective in excision repair to seven. The results are discussed relative to other genetic and biochemical properties of these mutants.

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Year:  1981        PMID： 6785044     DOI： 10.1007/BF00286109

Source DB:  PubMed          Journal:  Chromosoma        ISSN： 0009-5915            Impact factor:   4.316


  16 in total

1.  Fractionation of DNA from mammalian cells by alkaline elution.

Authors:  K W Kohn; L C Erickson; R A Ewig; C A Friedman
Journal:  Biochemistry       Date:  1976-10-19       Impact factor: 3.162

2.  THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISM.

Authors:  R B SETLOW; W L CARRIER
Journal:  Proc Natl Acad Sci U S A       Date:  1964-02       Impact factor: 11.205

3.  Isolation and identification of the irradiation product of thymine.

Authors:  R BEUKERS; W BERENDS
Journal:  Biochim Biophys Acta       Date:  1960-07-15

4.  Removal of pyrimidine dimers from Saccharomyces cerevisiae nuclear DNA under nongrowth conditions as detected by a sensitive, enzymatic assay.

Authors:  R J Reynolds
Journal:  Mutat Res       Date:  1978-04       Impact factor: 2.433

5.  Defective repair replication of DNA in xeroderma pigmentosum.

Authors:  J E Cleaver
Journal:  Nature       Date:  1968-05-18       Impact factor: 49.962

6.  The mei-9 alpha mutant of Drosophila melanogaster increases mutagen sensitivity and decreases excision repair.

Authors:  J B Boyd; M D Golino; R B Setlow
Journal:  Genetics       Date:  1976-11       Impact factor: 4.562

7.  Genetic controls of meiotic recombination and somatic DNA metabolism in Drosophila melanogaster.

Authors:  B S Baker; J B Boyd; A T Carpenter; M M Green; T D Nguyen; P Ripoll; P D Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1976-11       Impact factor: 11.205

8.  A seventh complementation group in excision-deficient xeroderma pigmentosum.

Authors:  W Keijzer; N G Jaspers; P J Abrahams; A M Taylor; C F Arlett; B Zelle; H Takebe; P D Kinmont; D Bootsma
Journal:  Mutat Res       Date:  1979-08       Impact factor: 2.433

9.  DNA repair in Potorous tridactylus.

Authors:  S N Buhl; R B Setlow; J D Regan
Journal:  Biophys J       Date:  1974-10       Impact factor: 4.033

10.  Excision repair in Drosophila. Analysis of strand breaks appearing in DNA of mei-9 mutants following mutagen treatment.

Authors:  P V Harris; J B Boyd
Journal:  Biochim Biophys Acta       Date:  1980-11-14
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  7 in total

1.  Isolation and characterization of a photorepair-deficient mutant in Drosophila melanogaster.

Authors:  J B Boyd; P V Harris
Journal:  Genetics       Date:  1987-06       Impact factor: 4.562

2.  Third-chromosome mutagen-sensitive mutants of Drosophila melanogaster.

Authors:  J B Boyd; M D Golino; K E Shaw; C J Osgood; M M Green
Journal:  Genetics       Date:  1981 Mar-Apr       Impact factor: 4.562

3.  Radiation-sensitive mutants of Caenorhabditis elegans.

Authors:  P S Hartman; R K Herman
Journal:  Genetics       Date:  1982-10       Impact factor: 4.562

4.  Postreplication repair defects in mutants of Drosophila melanogaster.

Authors:  J B Boyd; K E Shaw
Journal:  Mol Gen Genet       Date:  1982

5.  Mutagen sensitivity of Drosophila melanogaster. V. Identification of second chromosomal mutagen sensitive strains.

Authors:  R D Snyder; P D Smith
Journal:  Mol Gen Genet       Date:  1982

6.  Molecular cloning of eucaryotic genes required for excision repair of UV-irradiated DNA: isolation and partial characterization of the RAD3 gene of Saccharomyces cerevisiae.

Authors:  L Naumovski; E C Friedberg
Journal:  J Bacteriol       Date:  1982-10       Impact factor: 3.490

7.  The DNA polymerases of Drosophila melanogaster.

Authors:  Steven J Marygold; Helen Attrill; Elena Speretta; Kate Warner; Michele Magrane; Maria Berloco; Sue Cotterill; Mitch McVey; Yikang Rong; Masamitsu Yamaguchi
Journal:  Fly (Austin)       Date:  2020-01-14       Impact factor: 2.160
  7 in total

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