| Literature DB >> 492197 |
W Keijzer, N G Jaspers, P J Abrahams, A M Taylor, C F Arlett, B Zelle, H Takebe, P D Kinmont, D Bootsma.
Abstract
Cells from a xeroderma pigmentosum patient XP2BI who has reached 17 years of age with no keratoses or skin tumours constitute a new, 7th complementation group G. These cells exhibit a low residual level of excision repair, 2% of normal after a UV dose of 5 J/m2 and an impairment of post-replication repair characteristic of excision-defective XPs. They are also sensitive to the lethal effects of UV and defective in host-cell reactivation of UV-irradiated SV40 DNA.Entities:
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Year: 1979 PMID： 492197 DOI： 10.1016/0027-5107(79)90231-8
Source DB: PubMed Journal: Mutat Res ISSN： 0027-5107 Impact factor: 2.433