| Literature DB >> 6782080 |
J G Cannon, D G Klapper, E Y Blackman, P F Sparling.
Abstract
An increase in the apparent molecular weight of the principal outer membrane protein (POMP) of Neisseria gonorrhoeae is associated with introduction of the penB2 genetic marker, which results in low-level, relatively nonspecific antibiotic resistance. Limited proteolysis of the two forms of POMP showed that they had few if any peptides in common. The nonspecific antibiotic resistance of penB2 was separated from the change in POMP by genetic transformation and by isolation of spontaneous penB mutants that showed no change in POMP. The genetic locus involved in the change from one POMP to another, which we have designated nmp-1, is closely linked to, but not identical with, penB2.Entities:
Mesh：
Substances：
Year: 1980 PMID： 6782080 PMCID： PMC294376 DOI： 10.1128/jb.143.2.847-851.1980
Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490