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Literature DB >> 6779315

The effect of drug holidays in an animal model of tardive dyskinesia.

Abstract

Intermittent haloperidol treatment in mice increased 3H-spiroperidol binding to the same degree as continual haloperidol feeding. The results do not support the concept that drug holidays can reduce the incidence of tardive dyskinesia.

Entities: Chemical Disease Species

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Year: 1980 PMID： 6779315 DOI： 10.1007/bf00427654

Source DB: PubMed Journal: Psychopharmacology (Berl) ISSN： 0033-3158 Impact factor: 4.530

7 in total

1. Drug therapy of tardive dyskinesia.

Authors: R M Kobayashi
Journal: N Engl J Med Date: 1977-02-03 Impact factor: 91.245

2. Properties of [3H]haloperidol and [3H]dopamine binding associated with dopamine receptors in calf brain membranes.

Authors: D R Burt; I Creese; S H Snyder
Journal: Mol Pharmacol Date: 1976-09 Impact factor: 4.436

3. Behavioural supersensitivity to apomorphine following chronic treatment with drugs which interfere with the synaptic function of catecholamines.

Authors: D Tarsy; R J Baldessarini
Journal: Neuropharmacology Date: 1974-11 Impact factor: 5.250

4. Striatal dopamine receptors become supersensitive while rats are geven trifluoperazine for six months.

Authors: A Clow; P Jenner; A Theodorou; C D Marsden
Journal: Nature Date: 1979-03-01 Impact factor: 49.962

5. Dopamine receptor changes after long-term haloperidol treatment in rats.

Authors: R P Ebstein; D Pickholz; R H Belmaker
Journal: J Pharm Pharmacol Date: 1979-08 Impact factor: 3.765

6. Chronic high dose propranolol does not increase dopamine receptor number.

Authors: R P Ebstein; D Pickholz; S Sternberg; D Strajelevich; R H Belmaker
Journal: J Pharm Pharmacol Date: 1979-12 Impact factor: 3.765

7. Tardive dyskinesia--reversible and persistent.

Authors: D V Jeste; S G Potkin; S Sinha; S Feder; R J Wyatt
Journal: Arch Gen Psychiatry Date: 1979-05

7 in total

8 in total

8. Effects of discontinuous drug administration on the development of dopamine receptor supersensitivity during chronic trifluoperazine or cis-flupenthixol administration to rats.

Authors: K Murugaiah; A Theodorou; A Clow; P Jenner; C D Marsden
Journal: Psychopharmacology (Berl) Date: 1985 Impact factor: 4.530

8 in total

The effect of drug holidays in an animal model of tardive dyskinesia.

1. Drug therapy of tardive dyskinesia.

2. Properties of [3H]haloperidol and [3H]dopamine binding associated with dopamine receptors in calf brain membranes.

3. Behavioural supersensitivity to apomorphine following chronic treatment with drugs which interfere with the synaptic function of catecholamines.

4. Striatal dopamine receptors become supersensitive while rats are geven trifluoperazine for six months.

5. Dopamine receptor changes after long-term haloperidol treatment in rats.

6. Chronic high dose propranolol does not increase dopamine receptor number.

7. Tardive dyskinesia--reversible and persistent.

1. Intermittent and continuous haloperidol regimens produce different types of oral dyskinesias in rats.

2. Effects of intermittent haloperidol treatment on dopamine receptor sensitivity in guinea pigs.

3. Sensitization to haloperidol-induced suppression of milk intake: effect of interdose interval.

Review 4. Management of tardive dyskinesia: current update.

5. Treatment schedule as a determinant of the development of tolerance to haloperidol.

6. Progressive changes in the acute dyskinetic syndrome as a function of repeated elicitation in squirrel monkeys.

7. A depot neuroleptic withdrawal study neurological effects.

8. Effects of discontinuous drug administration on the development of dopamine receptor supersensitivity during chronic trifluoperazine or cis-flupenthixol administration to rats.