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Literature DB >> 6777462

Abnormal regulation of prolactin release in idiopathic Parkinson's disease.

Abstract

Levodopa with carbidopa suppressed prolactin release induced by thyrotrophin releasing hormone less effectively in patients with idiopathic Parkinson's disease than in normal subjects. This finding supports the view that the biochemical defect in idiopathic Parkinson's disease extends to the hypothalamus and is not confined to the basal ganglia. Aetiological considerations in Parkinson's disease should encompass a widespread disorder of neurotransmission whose extent merits further investigation.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 1980 PMID： 6777462 PMCID： PMC490753 DOI： 10.1136/jnnp.43.11.1012

Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154

12 in total

Review 1. Recent advances in the treatment of Parkinsonism with drugs.

Authors: U K Rinne
Journal: Acta Neurol Scand Suppl Date: 1972

Review 2. Dopamine in the basal ganglia. Its role and therapeutic implications (including the clinical use of L-DOPA).

Authors: O Hornykiewicz
Journal: Br Med Bull Date: 1973-05 Impact factor: 4.291

3. Suppression of prolactin release by a purified porcine PIF preparation and catecholamines infused into a rat hypophysial portal vessel.

Authors: J Takahara; A Arimura; A V Schally
Journal: Endocrinology Date: 1974-08 Impact factor: 4.736

4. A homologous radioimmunoassay for human prolactin.

Authors: Y N Sinha; F W Selby; U J Lewis; W P VanderLaan
Journal: J Clin Endocrinol Metab Date: 1973-03 Impact factor: 5.958

5. Levodopa suppression of prolactin in nonpuerperal galactorrhea.

Authors: W B Malarkey; L S Jacobs; W H Daughaday
Journal: N Engl J Med Date: 1971-11-18 Impact factor: 91.245

6. Parkinson's disease: activity of L-dopa decarboxylase in discrete brain regions.

Authors: K Lloyd; O Hornykiewicz
Journal: Science Date: 1970-12-11 Impact factor: 47.728

7. Dopamine is an important neurotransmitter in the autonomic nervous system.

Authors: M O Thorner
Journal: Lancet Date: 1975-03-22 Impact factor: 79.321

8. Interrelationships in the regulation of TSH and prolactin secretion in man: effects of L-dopa, TRH and thyroid hormone in various combinations.

Authors: S Refetoff; V S Fang; B Rapoport; H G Friesen
Journal: J Clin Endocrinol Metab Date: 1974-03 Impact factor: 5.958

Abnormal regulation of prolactin release in idiopathic Parkinson's disease.

Review 1. Recent advances in the treatment of Parkinsonism with drugs.

Review 2. Dopamine in the basal ganglia. Its role and therapeutic implications (including the clinical use of L-DOPA).

3. Suppression of prolactin release by a purified porcine PIF preparation and catecholamines infused into a rat hypophysial portal vessel.

4. A homologous radioimmunoassay for human prolactin.

5. Levodopa suppression of prolactin in nonpuerperal galactorrhea.

6. Parkinson's disease: activity of L-dopa decarboxylase in discrete brain regions.

7. Dopamine is an important neurotransmitter in the autonomic nervous system.

8. Interrelationships in the regulation of TSH and prolactin secretion in man: effects of L-dopa, TRH and thyroid hormone in various combinations.

9. Functional evaluation of prolactin secretion: a guide to therapy.

10. Long-term treatment of galactorrhoea and hypogonadism with bromocriptine.

1. Growth hormone and prolactin stimulation by Madopar in Parkinson's disease.

Review 2. The hypothalamus in Parkinson disease.

3. Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson's disease.

4. Proteomic Profile of Saliva in Parkinson's Disease Patients: A Proof of Concept Study.