Literature DB >> 6775583

Sodium valproate and bone marrow suppression.

F R Smith, M Boots.   

Abstract

Bone marrow suppression developed in a patient while she was on a regimen of sodium valproate. In addition, she had high titers of platelet autoantibodies and a coagulopathy, both recognized complications of valproate therapy. It is postulated that this drug was also responsible for the marrow suppression.

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Year:  1980        PMID： 6775583     DOI： 10.1002/ana.410080213

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  4 in total

Review 1.  Antiepileptic drug toxicity: definition and mechanism of action.

Authors:  E Beghi; R Di Mascio
Journal:  Ital J Neurol Sci       Date:  1986-04

2.  Bone marrow suppression induced by high dose valproic acid.

Authors:  T Kishi; N Fujita; H Kawaguchi; M Ishimae; K Watanabe; T Tanaka
Journal:  Arch Dis Child       Date:  1994-08       Impact factor: 3.791

3.  Targeting Bone Marrow to Potentiate the Anti-Tumor Effect of Tyrosine Kinase Inhibitor in Preclinical Rat Model of Human Glioblastoma.

Authors:  S Shaaban; M Alsulami; S A Arbab; R Ara; A Shankar; A Iskander; K Angara; M Jain; H Bagher-Ebadian; B R Achyut; A S Arbab
Journal:  Int J Cancer Res       Date:  2016-03-15

4.  Favorable results after conservative management of 316 valproate intoxicated patients.

Authors:  Shahin Shadnia; Hasan Amiri; Hossein Hassanian-Moghaddam; Mahdi Rezai; Zohreh Vasei; Nillofar Ghodrati; Nasim Zamani
Journal:  J Res Med Sci       Date:  2015-07       Impact factor: 1.852
  4 in total

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