Literature DB >> 6774887

Vanadate: non-selective inhibition of transepithelial transport of Na+, H+ and water.

D D Fanestil.   

Abstract

In the isolated urinary bladder of the toad, 10(-5)-10(-4)M orthovanadate produces inhibition of the active transport of Na+ and H+ ions as well as of antidiuretic hormone-mediated osmotic flow of water. Since transport of H+ ions and osmotic water flow are not inhibited when (Na+ + K+)-ATPase is inhibited by ouabain, biological actions of vanadate are not necessarily related to inhibition of (Na+ + K+)-ATPase.

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Year:  1980        PMID： 6774887     DOI： 10.1007/bf01965959

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  14 in total

1.  Importance of guanidinium groups of blocking sodium channels in epithelia.

Authors:  A W Cuthbert
Journal:  Mol Pharmacol       Date:  1976-11       Impact factor: 4.436

2.  Kinetics of inhibition of NaK-ATPase by Mg(2+), K+, and vanadate.

Authors:  G H Bond; P M Hudgins
Journal:  Biochemistry       Date:  1979-01-23       Impact factor: 3.162

3.  Commercial ATP containing traces of vanadate alters the response of (Na+ + K+) ATPase to external potassium.

Authors:  L A Beaugé; I M Glynn
Journal:  Nature       Date:  1978-04-06       Impact factor: 49.962

4.  Active transport of sodium as the source of electric current in the short-circuited isolated frog skin.

Authors:  H H USSING; K ZERAHN
Journal:  Acta Physiol Scand       Date:  1951-08-25

5.  Ionic and metabolic requirements for the hydroosmotic response to antidiuretic hormone in toad urinary bladder.

Authors:  W L Davis; D B Goodman; H Rasmussen
Journal:  J Membr Biol       Date:  1978-07-05       Impact factor: 1.843

6.  Vanadate-stimulated natriuresis.

Authors:  W E Balfour; J J Grantham; I M Glynn
Journal:  Nature       Date:  1978-10-26       Impact factor: 49.962

7.  Acidification of urine by the isolated urinary bladder of the toad.

Authors:  J H Ludens; D D Fanestil
Journal:  Am J Physiol       Date:  1972-12

8.  Sodium-specific membrane channels of frog skin are pores: current fluctuations reveal high turnover.

Authors:  B Lindemann; W Van Driessche
Journal:  Science       Date:  1977-01-21       Impact factor: 47.728

9.  Vanadate is a potent (Na,K)-ATPase inhibitor found in ATP derived from muscle.

Authors:  L C Cantley; L Josephson; R Warner; M Yanagisawa; C Lechene; G Guidotti
Journal:  J Biol Chem       Date:  1977-11-10       Impact factor: 5.157

10.  Amiloride: a potent inhibitor of sodium transport across the toad bladder.

Authors:  P J Bentley
Journal:  J Physiol       Date:  1968-03       Impact factor: 5.182
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  4 in total

1.  Common channels for water and protons at apical and basolateral cell membranes of frog skin and urinary bladder epithelia. Effects of oxytocin, heavy metals, and inhibitors of H(+)-adenosine triphosphatase.

Authors:  B Harvey; I Lacoste; J Ehrenfeld
Journal:  J Gen Physiol       Date:  1991-04       Impact factor: 4.086

2.  Vanadate and ouabain: a comparative study in toad skin.

Authors:  J Aboulafia; F Lacaz-Vieira
Journal:  Pflugers Arch       Date:  1984-06       Impact factor: 3.657

3.  Forskolin mimics the hydrosmotic action of vasopressin in the urinary bladder of toads Bufo marinus.

Authors:  R C De Sousa; A Grosso
Journal:  J Physiol       Date:  1985-08       Impact factor: 5.182

4.  Effect of chronic vanadate ingestion on amino acid and water absorption in rat intestine.

Authors:  J J Hajjar; M P Dobish; T K Tomicic
Journal:  Arch Toxicol       Date:  1989       Impact factor: 5.153
  4 in total

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