Literature DB >> 6774371

Motor depression and head twitches induced by IP injection of GABA.

A Smiałowski, M Smiałowska, K Reichenberg, B Byrska, J Vetulani.   

Abstract

Influence of GABA onlocomotor activity and gross behavior of mice, rats, and rabbits was studied. In mice and rats, IP GABA injection produced decreased locomotor activity, but in rats and rabbits head twitches and disturbances in body balance were seen. GABA-induced head twitches were inhibited by picrotoxin, clonidine, morphine, or cyproheptadine. Our results suggest a serotonergic component in GABA-induced head twitches, but it is not the only mechanism involved in this behavior.

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Year:  1980        PMID： 6774371     DOI： 10.1007/bf00433099

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  18 in total

1.  GAMMA-AMINOBUTYRIC ACID AND OXYGEN POISONING.

Authors:  J D WOOD; W J WATSON; F M CLYDESDALE
Journal:  J Neurochem       Date:  1963-09       Impact factor: 5.372

2.  The effect of intracerebroventricularly administered GABA on brain monoamine metabolism.

Authors:  B Biswas; A Carlsson
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-08       Impact factor: 3.000

3.  Depression by clonidine of shaking behaviour elicited by nalorphine in morphine-dependent rats.

Authors:  J Vetulani; B Bednarczyk
Journal:  J Pharm Pharmacol       Date:  1977-09       Impact factor: 3.765

4.  Stimulatory and inhibitory action of clonidine on the locomotor activity in the rat.

Authors:  B Bednarczyk; J Vetulani
Journal:  Pol J Pharmacol Pharm       Date:  1977 May-Jun

5.  Raised brain GABA levels, motor activity and exploration in the rat.

Authors:  S E File
Journal:  Brain Res       Date:  1977-08-05       Impact factor: 3.252

6.  A possible correlation between drug-induced hallucinations in man and a behavioural response in mice.

Authors:  S J Corne; R W Pickering
Journal:  Psychopharmacologia       Date:  1967

7.  [Pharmacological and experimental psychological studies with 2 components of fly agaric (Amanita muscaria)].

Authors:  W Theobald; O Büch; H A Kunz; P Krupp; E G Stenger; H Heimann
Journal:  Arzneimittelforschung       Date:  1968-03

8.  5-Methoxytryptamine-induced head twitches in rats.

Authors:  E Przegaliński; I Zebrowska-Lupina; A Wójcik; Z Kleinrok
Journal:  Pol J Pharmacol Pharm       Date:  1977 May-Jun

9.  A method for assessing the effects of drugs on the central actions of 5-hydroxytryptamine.

Authors:  S J CORNE; R W PICKERING; B T WARNER
Journal:  Br J Pharmacol Chemother       Date:  1963-02

10.  Indoleamine antagonists: relative potencies as inhibitors of tryptamine- and 5-hydroxytryptophan-evoked responses.

Authors:  B V Clineschmidt; V J Lotti
Journal:  Br J Pharmacol       Date:  1974-02       Impact factor: 8.739
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  3 in total

1.  Modulation of 5-hydroxytryptamine-induced head-twitch response by drugs acting at GABA and related receptors.

Authors:  S L Handley; L Singh
Journal:  Br J Pharmacol       Date:  1985-09       Impact factor: 8.739

2.  Involvement of noradrenaline in potentiation of the head-twitch response by GABA-related drugs.

Authors:  L Singh; J C Heaton; P J Rea; S L Handley
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

3.  The effects of dietary proline, β-alanine, and γ-aminobutyric acid (GABA) on the nest construction behavior in the Oriental hornet (Vespa orientalis).

Authors:  Sofia Bouchebti; Levona Bodner; Maya Bergman; Tali Magory Cohen; Eran Levin
Journal:  Sci Rep       Date:  2022-05-06       Impact factor: 4.996
  3 in total

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