Literature DB >> 6771294

Chemotherapy of autochthonous leukemias induced by 7,12-dimethylbenz(a)anthracene in Long Evans rats.

W J Zeller, M Berger, D Schmähl.   

Abstract

A total of 111 autochthonous (primary) acute rat leukemias of the diffuse-hepatic type which had been induced by 7.12-dimethylbenz(a)anthracene were treated with mono- and combination chemotherapy. The survival time of treated rats increased significantly compared to untreated controls. A combination of vincristine (VCR), adriamycin (ADR), and cytosine arabinoside (Ara-C) was superior to a combination of VCR and ADR as well as to a monotherapy with Cyclophosphamide, BCNU, VCR, ADR, and Ara-C.

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Year:  1980        PMID： 6771294     DOI： 10.1007/bf00405500

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN： 0171-5216            Impact factor:   4.553


  6 in total

1.  Leukemias induced by ethylnitrosourea in Wistar rats: incidence and chemotherapy.

Authors:  W J Zeller; D Schmähl
Journal:  Leuk Res       Date:  1979       Impact factor: 3.156

2.  Regression of stem-cell erythroblastic leukemia after hypophysectomy.

Authors:  C Huggins; H Oka
Journal:  Cancer Res       Date:  1972-02       Impact factor: 12.701

3.  Composition and preparation of experimental intravenous fat emulsions.

Authors:  P E Schurr
Journal:  Cancer Res       Date:  1969-01       Impact factor: 12.701

4.  Induction of leukemia in rat by pulse doses of 7,12-dimethylbenz(a)anthracene.

Authors:  C B Huggins; T Sugiyama
Journal:  Proc Natl Acad Sci U S A       Date:  1966-01       Impact factor: 11.205

5.  Examination of four newly synthesized 2-chloroethylnitrosoureas in comparison with BCNU, CCNU, MeCCNU, chlorozotocin and hydroxyethyl-CNU in preterminal rat leukemia L 5222.

Authors:  W J Zeller; G Eisenbrand; H H Fiebig
Journal:  J Cancer Res Clin Oncol       Date:  1979-09       Impact factor: 4.553

6.  Synergistic action of vincristine and adriamycin in the treatment of experimental rat leukemia L5222.

Authors:  W J Zeller; M Berger; D Schmähl
Journal:  Cancer Res       Date:  1979-03       Impact factor: 12.701
  6 in total
  5 in total

1.  Recovery patterns of rat hemopoietic stem cells between pulse doses of 7,12-dimethylbenz(a)anthracene (DMBA) applied in a leukemogenic regimen.

Authors:  I Fohlmeister; O Hohentanner; A Porr
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

2.  Antineoplastic activity of ASTA Z 7557 (INN mafosfamide) in transplanted and autochthonous experimental rodent tumors.

Authors:  W J Zeller; M R Berger; R Matys; J Schuhmacher
Journal:  Invest New Drugs       Date:  1984       Impact factor: 3.850

3.  Experimental chemotherapy with N'N'-bis(2-chloroethyl)-N-nitrosourea (BCNU) in autochthonous neurogenic tumors of the rat transplacentally induced by ethylnitrosourea.

Authors:  H H Fiebig; H Strobel; D Schmähl
Journal:  J Cancer Res Clin Oncol       Date:  1982       Impact factor: 4.553

4.  On the pathogenesis of preleukemic myelodysplastic syndromes: development of a dysplastic hemopoietic proliferation in the rat after a single pulse dose of dimethylbenz(a)anthracene (DMBA).

Authors:  I Fohlmeister; H E Schaefer; R Fischer
Journal:  J Cancer Res Clin Oncol       Date:  1982       Impact factor: 4.553

5.  Modulation of chemical carcinogenesis in rats by alkyl lysophospholipids.

Authors:  M R Berger; D Schmähl
Journal:  Lipids       Date:  1987-11       Impact factor: 1.880
  5 in total

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