Literature DB >> 6771006

Activation of Ftorafue [R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil] to 5-fluorouracil and gamma-butyrolactone.

J L Au, W Sadée.   

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Year:  1980        PMID: 6771006

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


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  11 in total

1.  Cytotoxicity of three novel fluoropyrimidines in cultured L1210 murine lymphocytic leukemia cells.

Authors:  A M Shipp; M H Holshouser; P W Ferguson
Journal:  Pharm Res       Date:  1990-12       Impact factor: 4.200

2.  Stereoselective metabolism of ftorafur (R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil).

Authors:  J L Au; W Sadée
Journal:  Cancer Chemother Pharmacol       Date:  1981       Impact factor: 3.333

3.  Hepatic conversion of 1-(tetrahydro-2-furanyl)-5-fluorouracil into 5-fluorouracil in patients with hepatocellular carcinoma.

Authors:  S Kawata; S Noda; Y Imai; S Tamura; R Saitoh; S Miyoshi; Y Minami; S Tarui
Journal:  Gastroenterol Jpn       Date:  1987-02

Review 4.  Tegafur/uracil + calcium folinate in colorectal cancer: double modulation of fluorouracil.

Authors:  P M Hoff; Y Lassere; R Pazdur
Journal:  Drugs       Date:  1999       Impact factor: 9.546

5.  A case of allergic liver injury induced by tegafur.

Authors:  M Baba; T Shima; T Tanaka; M Nakayabu; H Hasegawa; S Suzuki; I Kusano
Journal:  J Gastroenterol       Date:  1994-02       Impact factor: 7.527

6.  UFT and its metabolite gamma-butyrolactone (GBL) inhibit angiogenesis induced by vascular endothelial growth factor in advanced cervical carcinoma.

Authors:  Nobutaka Nagai; Keiji Mukai; Eiji Hirata; Hong Hua Jin; Masaaki Komatsu; Mayu Yunokawa
Journal:  Med Oncol       Date:  2007-10-30       Impact factor: 3.064

7.  Oral ftorafur plus intramuscular thiotepa as adjuvant chemotherapy in patients with breast cancer.

Authors:  C M Galmarini; C Garbovesky; D Galmarini; F C Galmarini
Journal:  Med Oncol       Date:  2002       Impact factor: 3.064

8.  Chronic active hepatitis and liver cirrhosis in association with combined tamoxifen/tegafur adjuvant therapy.

Authors:  S Maruyama; C Hirayama; J Abe; J Tanaka; K Matsui
Journal:  Dig Dis Sci       Date:  1995-12       Impact factor: 3.199

9.  Pharmacokinetics of ftorafur after intravenous and oral administration.

Authors:  M I Anttila; E A Sotaniemi; M I Kairaluoma; R E Mokka; H T Sundquist
Journal:  Cancer Chemother Pharmacol       Date:  1983       Impact factor: 3.333

10.  Oral tegafur in the treatment of gastrointestinal tract cancers: a phase II study.

Authors:  S Palmeri; V Gebbia; A Russo; M G Armata; N Gebbia; L Rausa
Journal:  Br J Cancer       Date:  1990-03       Impact factor: 7.640

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