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Literature DB >> 6770465

Prolongation of islet xenograft survival without continuous immunosuppression.

Abstract

The survival of isolated rat islets transplanted into diabetic mice was prolonged markedly by maintaining the rat islets in vitro at 24 degrees C for 7 days before transplantation and administering to the recipients a single injection of antiserum to mouse and rat lymphocytes shortly before transplantation.

Entities: Disease Species

Mesh：

Substances：
Blood Glucose

Year: 1980 PMID： 6770465 DOI： 10.1126/science.6770465

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

18 in total

1. Prevention of core cell damage in isolated islets of Langerhans by low temperature preconditioning.

Authors: Yun-Fu Cui; Ming Ma; Gui-Yu Wang; De-En Han; Brigitte Vollmar; Michael D Menger
Journal: World J Gastroenterol Date: 2005-01-28 Impact factor: 5.742

2. Transforming growth factor beta decreases the immunogenicity of rat islet xenografts (rat to mouse) and prevents rejection in association with treatment of the recipient with a monoclonal antibody to interferon gamma.

Authors: J C Carel; R D Schreiber; L Falqui; P E Lacy
Journal: Proc Natl Acad Sci U S A Date: 1990-02 Impact factor: 11.205

Prolongation of islet xenograft survival without continuous immunosuppression.

1. Prevention of core cell damage in isolated islets of Langerhans by low temperature preconditioning.

2. Transforming growth factor beta decreases the immunogenicity of rat islet xenografts (rat to mouse) and prevents rejection in association with treatment of the recipient with a monoclonal antibody to interferon gamma.

3. Induction of Pancreatic Islet Graft Acceptance: The Role of Antigen Presenting Cells.

Review 4. Pancreas and islet transplantation. I. Experimental studies.

5. Demonstration of active tolerance in maintenance of established islet of Langerhans allografts.

6. Experimental immuno-alteration.

7. Pancreatic islet transplantation: immuno-alteration with ultraviolet irradiation.

Review 8. Isolation and transplantation of islet tissue.

Review 9. Islet Culture/Preservation Before Islet Transplantation.

10. Prolongation of murine islet allograft survival by pretreatment of islets with antibody directed to Ia determinants.