Literature DB >> 6769613

Sex hormone changes in male epileptics.

B K Toone, M Wheeler, P B Fenwick.   

Abstract

Mean plasma levels of LH, FSH, PRL, and sex-hormone binding globulin (SHBG) were raised in twenty-seven epileptics on anticonvulsants compared with age matched controls. Sexual activity appeared to be reduced. Anticonvulsant therapy results in raised SHBG levels which may be associated with a lowered free testosterone level as indicated by raised LH levels and lowered sexual activity.

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Year:  1980        PMID： 6769613     DOI： 10.1111/j.1365-2265.1980.tb02726.x

Source DB:  PubMed          Journal:  Clin Endocrinol (Oxf)        ISSN： 0300-0664            Impact factor:   3.478


  8 in total

1.  Reduction of free testosterone by antiepileptic drugs.

Authors:  J Dana-Haeri; J Oxley; A Richens
Journal:  Br Med J (Clin Res Ed)       Date:  1982-01-09

2.  Endocrine function changes in young males during long-term antiepileptic therapy with phenobarbitone and carbamazepine.

Authors:  L Rozza; A Marcolla; G Ferrari
Journal:  Ital J Neurol Sci       Date:  1987-08

3.  Luteinizing hormone pulsatile secretion and pituitary response to gonadotropin releasing hormone and to thyrotropin releasing hormone in male epileptic subjects on chronic phenobarbital treatment.

Authors:  G Murialdo; R Manni; A De Maria; M L Bonura; A Polleri; A Tartara
Journal:  J Endocrinol Invest       Date:  1987-02       Impact factor: 4.256

4.  Gynecomastia in epileptics treated with phenobarbital, phenytoin and fluoresone: two case reports.

Authors:  L Rossi; U Bonuccelli; G Marcacci; A Bindi; G De Scisciolo; R Arena
Journal:  Ital J Neurol Sci       Date:  1983-06

5.  Effects of chlorpromazine and other drugs acting on the central nervous system on human sperm motility.

Authors:  C Y Hong; D M Chaput de Saintonge; P Turner
Journal:  Eur J Clin Pharmacol       Date:  1982       Impact factor: 2.953

6.  Induction of ovulation with pulsatile luteinising hormone releasing hormone.

Authors:  P Mason; J Adams; D V Morris; M Tucker; J Price; Z Voulgaris; Z M Van der Spuy; I Sutherland; G R Chambers; S White
Journal:  Br Med J (Clin Res Ed)       Date:  1984-01-21

7.  Sex hormones, sexual activity and plasma anticonvulsant levels in male epileptics.

Authors:  B K Toone; M Wheeler; M Nanjee; P Fenwick; R Grant
Journal:  J Neurol Neurosurg Psychiatry       Date:  1983-09       Impact factor: 10.154

8.  Changes in circulating androgens during short term carbamazepine therapy.

Authors:  J M Connell; W G Rapeport; G H Beastall; M J Brodie
Journal:  Br J Clin Pharmacol       Date:  1984-03       Impact factor: 4.335
  8 in total

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