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Literature DB >> 6766980

Cellular consequences in the suppression of antibody response by the antigen-specific T-cell factor.

Abstract

Cellular events mediated by antigen-specific soluble factor extracted from carrier-primed suppressor T cells (TsF) in the suppressive interaction was studied. Keyhole limpet hemocyanin (KLH)-specific TsF directly acts on KLH-primed, I-J positive, nylon-wool-adherent T cells that have an acceptor site for TsF. The nylon-wool-adherent T cells, after accepting TsF in the presence of specific antigen, generate new suppressor T cells acting as an actual effector cell type. Antigen-specificity and syngeneity at I-J between TsF and acceptor T cells are both required for the induction of new suppressor T cells. Newly induced suppressor T cells, however, suppress both syngeneic and allogeneic responses in an antigen-nonspecific fashion.

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Year: 1980 PMID： 6766980 PMCID： PMC2185813 DOI： 10.1084/jem.151.3.517

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

18 in total

1. The hydrogen ion dissociation curve of the crystalline albumin of the hen's egg.

Authors: R A Kekwick; R K Cannan
Journal: Biochem J Date: 1936-02 Impact factor: 3.857

2. Antigen-specific suppressive factor produced by a transplantable I-J bearing T-cell hybridoma.

Authors: M Taniguchi; T Saito; T Tada
Journal: Nature Date: 1979-04-05 Impact factor: 49.962

3. Regulatory mechanisms in cell-mediated immune responses. III. I-region control of suppressor cell interaction with responder cells in mixed lymphocyte reactions.

Authors: S S Rich; R R Rich
Journal: J Exp Med Date: 1976-03-01 Impact factor: 14.307

4. Cellular and genetic control of antibody responses. V. Helper T-cell recognition of H-2 determinants on accessory cells but not B cells.

Authors: A Singer; K S Hathcock; R J Hodes
Journal: J Exp Med Date: 1979-05-01 Impact factor: 14.307

5. Immunosuppressive factor(s) specific for L-glutamic acid50-L-tyrosine50 (GT). III. Generation of suppressor T cells by a suppressive extract derived from GT-primed lymphoid cells.

Authors: C Waltenbaugh; J Thèze; J A Kapp; B Benacerraf
Journal: J Exp Med Date: 1977-10-01 Impact factor: 14.307

6. Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. III. Dual gene control of the T-cell-mediated suppression of the antibody response.

Authors: M Taniguchi; T Tada; T Tokuhisa
Journal: J Exp Med Date: 1976-07-01 Impact factor: 14.307

7. Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. IV. Special subregion assignment of the gene(s) that codes for the suppressive T-cell factor in the H-2 histocompatibility complex.

Authors: T Tada; M Taniguchi; C S David
Journal: J Exp Med Date: 1976-09-01 Impact factor: 14.307

8. Suppressor-cell induction in vitro. IV. Target of antigen-specific suppressor factor and its genetic relationships.

Authors: S Kontiainen; M Feldmann
Journal: J Exp Med Date: 1978-01-01 Impact factor: 14.307

9. Cell interactions between histoincompatible T and B lymphocytes. II. Failure of physiologic cooperative interactions between T and B lymphocytes from allogeneic donor strains in humoral response to hapten-protein conjugates.

Authors: D H Katz; T Hamaoka; B Benacerraf
Journal: J Exp Med Date: 1973-06-01 Impact factor: 14.307

10. The role of macrophages in the generation of T-helper cells. II. The genetic control of the macrophage-T-cell interaction for helper cell induction with soluble antigens.

Authors: P Erb; M Feldmann
Journal: J Exp Med Date: 1975-08-01 Impact factor: 14.307

16 in total

1. Mechanism of MHC class II restriction in the interaction between specific suppressor and responder T cells in a proliferative response: Ia interaction with a putative anti-self receptor, expressed on pre-activated responder cells.

Authors: M B Zaitseva; B D Brondz
Journal: Immunology Date: 1990-07 Impact factor: 7.397

2. Characterization of an in vitro-stimulated, Cryptococcus neoformans-specific second-order suppressor T cell and its precursor.

Authors: P L Fidel; J W Murphy
Journal: Infect Immun Date: 1988-05 Impact factor: 3.441

Review 3. Antigen-specific T-cell factors.

Authors: M J Taussig
Journal: Immunology Date: 1980-12 Impact factor: 7.397

Review 4. Suppressor mechanisms in tumor immunity.

Authors: G T Nepom; I Hellström; K E Hellström
Journal: Experientia Date: 1983-03-15

Review 5. Idiotypes and autoimmunity.

Authors: I M Roitt; D K Male; A Cooke; P M Lydyard
Journal: Springer Semin Immunopathol Date: 1983

6. Purification and characterization of a monoclonal T-cell suppressor factor specific for poly(LGlu60LAla30LTyr10).

Authors: K Krupen; B A Araneo; L Brink; J A Kapp; S Stein; K J Wieder; D R Webb
Journal: Proc Natl Acad Sci U S A Date: 1982-02 Impact factor: 11.205

7. Specific suppression of antibody responses in vivo. I. Effects of in vitro produced suppressor factor.

Authors: S Kontiainen; I Todd; M Feldmann
Journal: Immunology Date: 1982-03 Impact factor: 7.397

8. Adoptive transfer of suppression of arthritis in the mouse model of collagen-induced arthritis. Evidence for a type II collagen-specific suppressor T cell.

Authors: T F Kresina; R W Moskowitz
Journal: J Clin Invest Date: 1985-06 Impact factor: 14.808

9. I-J restrictions on the activation and interaction of parental and F1-derived TS3 suppressor cells.

Authors: M Minami; S Furusawa; M E Dorf
Journal: J Exp Med Date: 1982-08-01 Impact factor: 14.307

10. Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

Authors: S C Meuer; K A Fitzgerald; R E Hussey; J C Hodgdon; S F Schlossman; E L Reinherz
Journal: J Exp Med Date: 1983-02-01 Impact factor: 14.307