Comparison of four commercial Tc-99m(Sn)DTPA preparations used for the measurement of glomerular filtration rate: concise communication.

To find a commercially available DTPA preparation that could be used for the measurement of glomerular filtration rate (GFR), the plasma clearances of four different Tc-99m(Sn)DTPA preparations were compared with that of Cr-51 EDTA using a single-injection technique. One preparation yielded results identical to those obtained with Cr-51 EDTA, whereas the others underestimated the GFR to a varying degree. It is concluded that Tc-99m DTPA can be used to estimate the GFR, but that the accuracy will depend on the commercial source.