Literature DB >> 6765595

Characterization of a 40S ribosomal subunit complex in polyribosomes of Saccharomyces cerevisiae treated with cycloheximide.

T L Helser1, R A Baan, A E Dahlberg.   

Abstract

Under specific conditions cycloheximide treatment of Saccharomyces cerevisiae caused the accumulation of a type of polyribosome called "halfmer." Limited ribonuclease digestion of halfmers released particles from the polyribosomes identified as 40S ribosomal subunits. The data demonstrated that halfmers are polyribosomes containing an additional 40S ribosomal subunit attached to the messenger ribonucleic acid. Protein gel electrophoretic analysis of halfmers revealed numerous nonribosomal proteins. Two of these proteins comigrate with subunits of yeast initiation factor eIF2.

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Year:  1981        PMID： 6765595      PMCID： PMC369326          DOI： 10.1128/mcb.1.1.51-57.1981

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  34 in total

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Authors:  B Safer; W F Anderson
Journal:  CRC Crit Rev Biochem       Date:  1978

2.  On the mechanisms of inhibition of polypeptide synthesis by the antibiotics sparsomycin and pactamycin.

Authors:  I H Goldberg; M L Stewart; M Ayuso; L S Kappen
Journal:  Fed Proc       Date:  1973-06

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Authors:  T E Martin
Journal:  Exp Cell Res       Date:  1973-08       Impact factor: 3.905

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

5.  Temperature-sensitive mutants of yeast exhibiting a rapid inhibition of protein synthesis.

Authors:  L H Hartwell; C S McLaughlin
Journal:  J Bacteriol       Date:  1968-11       Impact factor: 3.490

6.  The mechanism of sodium fluoride and cycloheximide inhibition of hemoglobin biosynthesis in the cell-free reticulocyte system.

Authors:  S Y Lin; R D Mosteller; B Hardesty
Journal:  J Mol Biol       Date:  1966-10-28       Impact factor: 5.469

7.  Macromolecule synthesis in yeast spheroplasts.

Authors:  H T Hutchison; L H Hartwell
Journal:  J Bacteriol       Date:  1967-11       Impact factor: 3.490

8.  The preparation and characterization of a cell-free system from Saccharomyces cerevisiae that translates natural messenger ribonucleic acid.

Authors:  E Gasior; F Herrera; I Sadnik; C S McLaughlin; K Moldave
Journal:  J Biol Chem       Date:  1979-05-25       Impact factor: 5.157

9.  The ribosomal proteins of Saccharomyces cerevisiae. Phosphorylated and exchangeable proteins.

Authors:  S Zinker; J R Warner
Journal:  J Biol Chem       Date:  1976-03-25       Impact factor: 5.157

10.  Macromolecule synthesis in temperature-sensitive mutants of yeast.

Authors:  L H Hartwell
Journal:  J Bacteriol       Date:  1967-05       Impact factor: 3.490
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  45 in total

1.  Qsr1p, a 60S ribosomal subunit protein, is required for joining of 40S and 60S subunits.

Authors:  D P Eisinger; F A Dick; B L Trumpower
Journal:  Mol Cell Biol       Date:  1997-09       Impact factor: 4.272

2.  Saccharomyces cerevisiae Nip7p is required for efficient 60S ribosome subunit biogenesis.

Authors:  N I Zanchin; P Roberts; A DeSilva; F Sherman; D S Goldfarb
Journal:  Mol Cell Biol       Date:  1997-09       Impact factor: 4.272

3.  SQT1, which encodes an essential WD domain protein of Saccharomyces cerevisiae, suppresses dominant-negative mutations of the ribosomal protein gene QSR1.

Authors:  D P Eisinger; F A Dick; E Denke; B L Trumpower
Journal:  Mol Cell Biol       Date:  1997-09       Impact factor: 4.272

4.  Ribosome recycling step in yeast cytoplasmic protein synthesis is catalyzed by eEF3 and ATP.

Authors:  Shinya Kurata; Klaus H Nielsen; Sarah F Mitchell; Jon R Lorsch; Akira Kaji; Hideko Kaji
Journal:  Proc Natl Acad Sci U S A       Date:  2010-06-01       Impact factor: 11.205

5.  GCD2, a translational repressor of the GCN4 gene, has a general function in the initiation of protein synthesis in Saccharomyces cerevisiae.

Authors:  M Foiani; A M Cigan; C J Paddon; S Harashima; A G Hinnebusch
Journal:  Mol Cell Biol       Date:  1991-06       Impact factor: 4.272

6.  Cold stress-induced protein Rbm3 binds 60S ribosomal subunits, alters microRNA levels, and enhances global protein synthesis.

Authors:  John Dresios; Armaz Aschrafi; Geoffrey C Owens; Peter W Vanderklish; Gerald M Edelman; Vincent P Mauro
Journal:  Proc Natl Acad Sci U S A       Date:  2005-01-31       Impact factor: 11.205

7.  RNA polymerase II elongation factors Spt4p and Spt5p play roles in transcription elongation by RNA polymerase I and rRNA processing.

Authors:  D A Schneider; S L French; Y N Osheim; A O Bailey; L Vu; J Dodd; J R Yates; A L Beyer; M Nomura
Journal:  Proc Natl Acad Sci U S A       Date:  2006-08-14       Impact factor: 11.205

8.  The specialized cytosolic J-protein, Jjj1, functions in 60S ribosomal subunit biogenesis.

Authors:  Alison E Meyer; Nai-Jung Hung; Peizhen Yang; Arlen W Johnson; Elizabeth A Craig
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-22       Impact factor: 11.205

9.  Ribosomal protein L33 is required for ribosome biogenesis, subunit joining, and repression of GCN4 translation.

Authors:  Pilar Martín-Marcos; Alan G Hinnebusch; Mercedes Tamame
Journal:  Mol Cell Biol       Date:  2007-06-04       Impact factor: 4.272

10.  The cytosolic J-protein, Jjj1, and Rei1 function in the removal of the pre-60 S subunit factor Arx1.

Authors:  Alison E Meyer; Lindsey A Hoover; Elizabeth A Craig
Journal:  J Biol Chem       Date:  2009-11-09       Impact factor: 5.157
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