Literature DB >> 6765503

Effects of pyridoxine and magnesium on autistic symptoms--initial observations.

G Lelord, J P Muh, C Barthelemy, J Martineau, B Garreau, E Callaway.   

Abstract

In an open trial, a heterogeneous group of 44 children with autistic symptoms were treated with large doses of vitamin B6 and magnesium. Clinical improvement with worsening on termination of the trial was observed in 15 children. Thirteen responders and 8 nonresponders were retested in a 2-week, crossover, double-blind trial, and the responses to the open trial were confirmed.

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Year:  1981        PMID： 6765503     DOI： 10.1007/bf01531686

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN： 0162-3257


  8 in total

1.  A rapid and simple gas-liquid chromatographic procedure for homovanillic and vanillylmandelic acid in urine.

Authors:  M S Roginsky; R D Gordon; M J Bennett
Journal:  Clin Chim Acta       Date:  1974-11-08       Impact factor: 3.786

2.  Magnesium in affective disorders.

Authors:  D Pavlinac; R Langer; L Lenhard; L Deftos
Journal:  Biol Psychiatry       Date:  1979-08       Impact factor: 13.382

3.  Subacute toxicity of pyridoxine hydrochloride in the beagle dog.

Authors:  W E Phillips; J H Mills; S M Charbonneau; L Tryphonas; G V Hatina; Z Zawidzka; F R Bryce; I C Munro
Journal:  Toxicol Appl Pharmacol       Date:  1978-05       Impact factor: 4.219

4.  Serum calcium and magnesium levels in schizophrenia. II. Possible relationship to extrapyramidal symptoms.

Authors:  P E Alexander; D P van Kammen; W E Bunney
Journal:  Arch Gen Psychiatry       Date:  1979-11

5.  The effect of high doses of vitamin B6 on autistic children: a double-blind crossover study.

Authors:  B Rimland; E Callaway; P Dreyfus
Journal:  Am J Psychiatry       Date:  1978-04       Impact factor: 18.112

6.  [Modifications in urinary homovanillic acid after ingestion of vitamin B6; functional study in autistic children (author's transl)].

Authors:  G Lelord; E Callaway; J P Muh; J C Arlot; D Sauvage; B Garreau; J Domenech
Journal:  Rev Neurol (Paris)       Date:  1978-12       Impact factor: 2.607

7.  Event-related potentials evoked by sensory stimulation in normal mentally retarded and autistic children.

Authors:  J Martineau; F Laffont; N Bruneau; S Roux; G Lelord
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1980-02

8.  Gas chromatographic determination of urinary vanilglycolic acid, vanilglycol, vanilacetic acid and vanillactic acid-chemical parameters for the diagnosis of neurogenic tumours and the evaluation of their treatment.

Authors:  S K Wadman; D Ketting; P A Voûte
Journal:  Clin Chim Acta       Date:  1976-10-01       Impact factor: 3.786
  8 in total
  24 in total

1.  Sensitivity and specificity of the Behavioral Summarized Evaluation (BSE) for the assessment of autistic behaviors.

Authors:  C Barthélémy; J L Adrien; S Roux; B Garreau; A Perrot; G Lelord
Journal:  J Autism Dev Disord       Date:  1992-03

Review 2.  Prognosis in autism: do specialist treatments affect long-term outcome?

Authors:  P Howlin
Journal:  Eur Child Adolesc Psychiatry       Date:  1997-06       Impact factor: 4.785

3.  Brief report: an open middle-term study of combined vitamin B6-magnesium in a subgroup of autistic children selected on their sensitivity to this treatment.

Authors:  J Martineau; C Barthelemy; C Cheliakine; G Lelord
Journal:  J Autism Dev Disord       Date:  1988-09

4.  Brief report: lack of response in an autistic population to a low dose clinical trial of pyridoxine plus magnesium.

Authors:  L Tolbert; T Haigler; M M Waits; T Dennis
Journal:  J Autism Dev Disord       Date:  1993-03

Review 5.  Efficacy of vitamin B6 and magnesium in the treatment of autism: a methodology review and summary of outcomes.

Authors:  S I Pfeiffer; J Norton; L Nelson; S Shott
Journal:  J Autism Dev Disord       Date:  1995-10

6.  Association study with two markers of a human homeogene in infantile autism.

Authors:  E Petit; J Hérault; J Martineau; A Perrot; C Barthélémy; L Hameury; D Sauvage; G Lelord; J P Müh
Journal:  J Med Genet       Date:  1995-04       Impact factor: 6.318

Review 7.  Early detection of autism. Diagnostic instruments for clinicians.

Authors:  C Gillberg; V Nordin; S Ehlers
Journal:  Eur Child Adolesc Psychiatry       Date:  1996-06       Impact factor: 4.785

8.  The Behavioral Summarized Evaluation: validity and reliability of a scale for the assessment of autistic behaviors.

Authors:  C Barthelemy; J L Adrien; P Tanguay; B Garreau; J Fermanian; S Roux; D Sauvage; G Lelord
Journal:  J Autism Dev Disord       Date:  1990-06

9.  The presence or absence of certain behaviors associated with infantile autism in severely retarded autistic and nonautistic retarded children and very young normal children.

Authors:  J L Adrien; E Ornitz; C Barthelemy; D Sauvage; G Lelord
Journal:  J Autism Dev Disord       Date:  1987-09

10.  Validity and reliability of the infant behavioral summarized evaluation (IBSE): a rating scale for the assessment of young children with autism and developmental disorders.

Authors:  J L Adrien; C Barthélémy; A Perrot; S Roux; P Lenoir; L Hameury; D Sauvage
Journal:  J Autism Dev Disord       Date:  1992-09
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