Literature DB >> 6765072

Thiamin in the elderly--relation to alcoholism and to neurological degenerative disease.

F L Iber, J P Blass, M Brin, C M Leevy.   

Abstract

Status of thiamin in the elderly North American population is reviewed. Most Americans eat sufficient thiamin but about 5% of those over 60 yr old show impaired thiamin status. This is more marked in the poor, those confined in institutions, or those with illness. Thiamin responsive heart disease and Wernicke Korsakoff CNS syndromes occur in the elderly but there is no increased prevalence. Minor heart or neurological syndromes related to thiamin deficiency cannot be identified. The Recommended Dietary Allowance of thiamin provides at least 50% excess thiamin for those over 60 yr old--this amount is adequate. There is no known toxicity for thiamin.

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Year:  1982        PMID: 6765072     DOI: 10.1093/ajcn/36.5.1067

Source DB:  PubMed          Journal:  Am J Clin Nutr        ISSN: 0002-9165            Impact factor:   7.045


  5 in total

Review 1.  Nutrition and the older adult.

Authors:  E Granieri
Journal:  Dysphagia       Date:  1990       Impact factor: 3.438

2.  Thiamine status in humans and content of phosphorylated thiamine derivatives in biopsies and cultured cells.

Authors:  Marjorie Gangolf; Jan Czerniecki; Marc Radermecker; Olivier Detry; Michelle Nisolle; Caroline Jouan; Didier Martin; Frédéric Chantraine; Bernard Lakaye; Pierre Wins; Thierry Grisar; Lucien Bettendorff
Journal:  PLoS One       Date:  2010-10-25       Impact factor: 3.240

3.  GABA-transaminase and glutamic acid decarboxylase changes in the brain of rats treated with pyrithiamine.

Authors:  S G Thompson; E G McGeer
Journal:  Neurochem Res       Date:  1985-12       Impact factor: 3.996

4.  A retrospective investigation of thiamin and energy intakes following an outbreak of beriberi in The Gambia.

Authors:  David I Thurnham; Angela E Cathcart; Margaret B E Livingstone
Journal:  Nutrients       Date:  2011-01-19       Impact factor: 5.717

5.  Clinical correlates and outcome of shoshin beriberi.

Authors:  Rama Prakasha Saya; Shashidhar Baikunje; Parampalli Suryanarayana Prakash; Kodangala Subramanyam; Vikram Patil
Journal:  N Am J Med Sci       Date:  2012-10
  5 in total

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