Literature DB >> 6758110

Quantitation of cells secreting immunoglobulins after elution from rheumatoid synovial tissue.

T Egeland, T Lea, O J Mellbye, J A Pahle, T Ottesen, J B Natvig.   

Abstract

Mononuclear cells (MNC) eluted from rheumatoid synovial tissue of 16 patients with rheumatoid arthritis were examined for immunoglobulin-secreting cells (ISC). Immediately after elution and separation synovial tissue MNC contained considerable numbers of ISC. IgG and IgA ISC were more abundant than IgM ISC. At the same time there were low numbers of ISC in blood. Synovial tissue ISC were lost during incubation with pokeweek mitogen (PWM), possibly because tissue MNC were already maximally triggered in vivo. This was in contrast to blood MNC, in which the number of ISC increased significantly during incubation with PWM.

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Year:  1982        PMID： 6758110     DOI： 10.1111/j.1365-3083.1982.tb00741.x

Source DB:  PubMed          Journal:  Scand J Immunol        ISSN： 0300-9475            Impact factor:   3.487


  9 in total

Review 1.  The B cell system in the rheumatoid inflammation. New insights into the pathogenesis of rheumatoid arthritis using synovial B cell hybridoma clones.

Authors:  J B Natvig; I Randen; K Thompson; O Førre; E Munthe
Journal:  Springer Semin Immunopathol       Date:  1989

2.  Immunoregulatory lymphokines in rheumatoid joints. II. Production by and responsiveness to interleukin-2 of eluted synovial tissue cells.

Authors:  J Hovdenes; T Egeland
Journal:  Rheumatol Int       Date:  1987       Impact factor: 2.631

3.  Effect of drug therapy on circulating and synovial fluid Ig-secreting cells in rheumatoid arthritis.

Authors:  S Al-Balaghi; H Ström; E Möller
Journal:  Ann Rheum Dis       Date:  1985-04       Impact factor: 19.103

4.  Human monoclonal rheumatoid factors derived from the polyclonal repertoire of rheumatoid synovial tissue: production and characterization.

Authors:  I Randen; K M Thompson; J B Natvig; O Førre; K Waalen
Journal:  Clin Exp Immunol       Date:  1989-10       Impact factor: 4.330

5.  In the rheumatoid pannus, anti-filaggrin autoantibodies are produced by local plasma cells and constitute a higher proportion of IgG than in synovial fluid and serum.

Authors:  C Masson-Bessière; M Sebbag; J J Durieux; L Nogueira; C Vincent; E Girbal-Neuhauser; R Durroux; A Cantagrel; G Serre
Journal:  Clin Exp Immunol       Date:  2000-03       Impact factor: 4.330

6.  Eluted rheumatoid synovial tissue T cell subsets and HLA-DR bearing cells at different stages of fractionation.

Authors:  T Egeland; O Førre
Journal:  Clin Rheumatol       Date:  1983-03       Impact factor: 2.980

7.  Phenotypic characterization of 3H-thymidine incorporating cells in rheumatoid arthritis synovial membrane.

Authors:  P Nykänen; V Bergroth; P Raunio; D Nordström; Y T Konttinen
Journal:  Rheumatol Int       Date:  1986       Impact factor: 2.631

8.  Subclasses of IgG produced in the rheumatoid synovium.

Authors:  O J Mellbye; F Vartdal; J H Dobloug
Journal:  Rheumatol Int       Date:  1984       Impact factor: 2.631

9.  Elevated autoantibody content in rheumatoid arthritis synovia with lymphoid aggregates and the effect of rituximab.

Authors:  Sanna Rosengren; Nathan Wei; Kenneth C Kalunian; Nathan J Zvaifler; Arthur Kavanaugh; David L Boyle
Journal:  Arthritis Res Ther       Date:  2008-09-01       Impact factor: 5.156
  9 in total

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