Literature DB >> 6744887

Confidence estimation and the size of a clinical trial.

R B McHugh, C T Le.   

Abstract

The general procedure for sample size determination based upon the confidence interval approach is reviewed and presented for both absolute and relative precision stipulations. The relationship between precision and sample size is discussed and methods for sample size determination for clinical trials are presented and illustrated with numerical examples.

Mesh:

Year:  1984        PMID: 6744887     DOI: 10.1016/0197-2456(84)90121-1

Source DB:  PubMed          Journal:  Control Clin Trials        ISSN: 0197-2456


  3 in total

1.  Confidence intervals and sample sizes: don't throw out all your old sample size tables.

Authors:  L E Daly
Journal:  BMJ       Date:  1991-02-09

2.  Sample size and power for comparing two or more treatment groups in clinical trials.

Authors:  S J Day; D F Graham
Journal:  BMJ       Date:  1989-09-09

3.  Clinical and statistical issues in therapeutic equivalence trials.

Authors:  E Garbe; J Röhmel; U Gundert-Remy
Journal:  Eur J Clin Pharmacol       Date:  1993       Impact factor: 2.953

  3 in total

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