Literature DB >> 6743663

Inhibition of rabbit liver arylsulfatase B by phosphate esters.

G J Rao, M E Christe.   

Abstract

Arylsulfatase B (aryl-sulfate sulfohydrolase, EC 3.1.6.1) purified from rabbit liver is competitively inhibited at modest concentrations by a variety of phosphate esters derived from amino acids, amines and simple sugars. Phospho-L-serine coupled to Sepharose 4B could be used as an affinity column to enhance the purity of a crude preparation of the enzyme. It is suggested that phosphate esters containing functional groups can be used to obtain affinity reagents to purify arylsulfatases and also to probe their active sites.

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Year:  1984        PMID: 6743663     DOI: 10.1016/0167-4838(84)90297-8

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  7 in total

1.  Reduced Arylsulfatase B activity in leukocytes from cystic fibrosis patients.

Authors:  Girish Sharma; Jenifer Burke; Sumit Bhattacharyya; Neha Sharma; Shivani Katyal; R Lucy Park; Joanne Tobacman
Journal:  Pediatr Pulmonol       Date:  2012-05-01

2.  Exposure to common food additive carrageenan leads to reduced sulfatase activity and increase in sulfated glycosaminoglycans in human epithelial cells.

Authors:  Bo Yang; Sumit Bhattacharyya; Robert Linhardt; Joanne Tobacman
Journal:  Biochimie       Date:  2012-03-05       Impact factor: 4.079

3.  Impact of salt exposure on N-acetylgalactosamine-4-sulfatase (arylsulfatase B) activity, glycosaminoglycans, kininogen, and bradykinin.

Authors:  Kumar Kotlo; Sumit Bhattacharyya; Bo Yang; Leonid Feferman; Shah Tejaskumar; Robert Linhardt; Robert Danziger; Joanne K Tobacman
Journal:  Glycoconj J       Date:  2013-02-06       Impact factor: 2.916

4.  A specific fluorogenic assay for N-acetylgalactosamine-4-sulphatase activity using immunoadsorption.

Authors:  D A Brooks; G J Gibson; P A McCourt; J J Hopwood
Journal:  J Inherit Metab Dis       Date:  1991       Impact factor: 4.982

5.  Arylsulfatase B regulates versican expression by galectin-3 and AP-1 mediated transcriptional effects.

Authors:  S Bhattacharyya; L Feferman; J K Tobacman
Journal:  Oncogene       Date:  2013-11-18       Impact factor: 9.867

6.  Inhibition of Phosphatase Activity Follows Decline in Sulfatase Activity and Leads to Transcriptional Effects through Sustained Phosphorylation of Transcription Factor MITF.

Authors:  Sumit Bhattacharyya; Leo Feferman; Joanne K Tobacman
Journal:  PLoS One       Date:  2016-04-14       Impact factor: 3.240

7.  Chondroitin sulfatases differentially regulate Wnt signaling in prostate stem cells through effects on SHP2, phospho-ERK1/2, and Dickkopf Wnt signaling pathway inhibitor (DKK3).

Authors:  Sumit Bhattacharyya; Leo Feferman; Joanne K Tobacman
Journal:  Oncotarget       Date:  2017-10-27
  7 in total

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