| Literature DB >> 6743494 |
A Hutchings, R D Monie, B Spragg, P A Routledge.
Abstract
In twelve healthy drug-free subjects (six slow acetylators), administration of alcohol (to achieve an ethanol concentration between 650 and 1180 mg 1(-1) ) did not significantly affect the ratio of monoacetyl dapsone (MADS) to dapsone (DDS) 3 h after oral dapsone (100 mg). We conclude that moderate acute ethanol consumption is unlikely to alter the acetylator phenotype measured by the dapsone test.Entities:
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Year: 1984 PMID： 6743494 PMCID： PMC1463575 DOI： 10.1111/j.1365-2125.1984.tb05029.x
Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335