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Literature DB >> 6743481

Cortisol and dexamethasone elimination during treatment with cimetidine.

N R Peden, I Rewhorn, M C Champion, R Mussani, T C Ooi.

Abstract

In a randomised cross-over study of treatment for 7 days with cimetidine 600 mg twice daily and placebo, cimetidine had no effect on the pharmacokinetics of a single intravenous dose of dexamethasone sodium phosphate. Likewise the elimination characteristics of endogenous cortisol in the dexamethasone suppressed state were not affected by cimetidine.

Entities: Chemical

Mesh：

Substances：

Year: 1984 PMID： 6743481 PMCID： PMC1463590 DOI： 10.1111/j.1365-2125.1984.tb05030.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

12 in total

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Authors: J Feely; D Robertson; D P Island; A J Wood
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Review 5. Assessment of urinary 6 beta-hydroxycortisol as an in vivo index of mixed-function oxygenase activity.

Authors: B K Park
Journal: Br J Clin Pharmacol Date: 1981-08 Impact factor: 4.335

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Authors: J Messer; D Reitman; H S Sacks; H Smith; T C Chalmers
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10. Changes in cortisol metabolism following rifampicin therapy.

Authors: O M Edwards; R J Courtenay-Evans; J M Galley; J Hunter; A D Tait
Journal: Lancet Date: 1974-09-07 Impact factor: 79.321

5 in total

Review 1. Clinical pharmacokinetics of drugs used in the treatment of gastrointestinal diseases (Part II).

Authors: K Lauritsen; L S Laursen; J Rask-Madsen
Journal: Clin Pharmacokinet Date: 1990-08 Impact factor: 6.447

2. Cimetidine and ranitidine on basal and ACTH-stimulated steroidogenesis.

Authors: R G Karlstadt; W O Frank; L A Antell; S W Shapowal; R H Palmer
Journal: Gut Date: 1987-12 Impact factor: 23.059

Review 3. Clinical pharmacokinetic considerations in the treatment of increased intracranial pressure.

Authors: G Heinemeyer
Journal: Clin Pharmacokinet Date: 1987-07 Impact factor: 6.447

Review 4. Pharmacokinetic interactions of cimetidine 1987.

Authors: A Somogyi; M Muirhead
Journal: Clin Pharmacokinet Date: 1987-05 Impact factor: 6.447

Review 5. Adverse reactions and interactions with H2-receptor antagonists.

Authors: J Penston; K G Wormsley
Journal: Med Toxicol Date: 1986 May-Jun

5 in total