Literature DB >> 6743236

Selective induction of glutathione S-transferase D in rat testis by phenobarbital.

D Sheehan, C M Ryle, T J Mantle.   

Abstract

Testis cytosol is shown to contain the Yb2Yb2 -homodimer glutathione S-transferase D in addition to the previously described glutathione S-transferases A ( Yb1Yb1 ) and C ( Yb1Yb2 ). Treatment of rats with phenobarbital induces the level of glutathione S-transferase D in testis with no increase in the activities of glutathione S-transferases A and C. This result indicates a specific induction of the Yb2 subunit in testis, in contrast with the situation in rat liver, where phenobarbital specifically induces the Yb1 subunit.

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Year:  1984        PMID： 6743236      PMCID： PMC1153528          DOI： 10.1042/bj2190687

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  7 in total

1.  Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.

Authors:  W H Habig; M J Pabst; W B Jakoby
Journal:  J Biol Chem       Date:  1974-11-25       Impact factor: 5.157

2.  Subunit composition of rat liver glutathione S-transferases.

Authors:  C P Tu; M J Weiss; C C Reddy
Journal:  Biochem Biophys Res Commun       Date:  1982-09-30       Impact factor: 3.575

3.  Binary combinations of four protein subunits with different catalytic specificities explain the relationship between six basic glutathione S-transferases in rat liver cytosol.

Authors:  B Mannervik; H Jensson
Journal:  J Biol Chem       Date:  1982-09-10       Impact factor: 5.157

4.  Tissue distribution and subunit structures of the multiple forms of glutathione S-transferase in the rat.

Authors:  N C Scully; T J Mantle
Journal:  Biochem J       Date:  1981-01-01       Impact factor: 3.857

5.  Rat liver glutathione S-transferases. A study of the structure of the basic YbYb-containing enzymes.

Authors:  J D Hayes
Journal:  Biochem J       Date:  1983-09-01       Impact factor: 3.857

6.  Evidence for two forms of ligandin (YaYa dimers of glutathione S-transferase) in rat liver and kidney.

Authors:  D Sheehan; T J Mantle
Journal:  Biochem J       Date:  1984-03-15       Impact factor: 3.857

7.  Identification of two lithocholic acid-binding proteins. Separation of ligandin from glutathione S-transferase B.

Authors:  J D Hayes; R C Strange; I W Percy-Robb
Journal:  Biochem J       Date:  1979-09-01       Impact factor: 3.857
  7 in total
  3 in total

1.  Purification and characterization of glutathione S-transferases P, S and N. Isolation from rat liver of Yb1 Yn protein, the existence of which was predicted by subunit hybridization in vitro.

Authors:  J D Hayes
Journal:  Biochem J       Date:  1984-12-15       Impact factor: 3.857

2.  Effects of dietary broccoli on rat testicular xenobiotic metabolizing enzymes.

Authors:  O Vang; K Mehrota; A Georgellis; O Andersen
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1999 Oct-Dec       Impact factor: 2.441

3.  A subclass of glutathione S-transferases as intracellular high-capacity and high-affinity steroid-binding proteins.

Authors:  H Homma; H Maruyama; Y Niitsu; I Listowsky
Journal:  Biochem J       Date:  1986-05-01       Impact factor: 3.857
  3 in total

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