Literature DB >> 6615452

Rat liver glutathione S-transferases. A study of the structure of the basic YbYb-containing enzymes.

J D Hayes.   

Abstract

A purification scheme was devised that resulted in the resolution of a number of basic glutathione S-transferases from rat liver, three of which contained two subunits of molecular mass 23500 Da (i.e. Yb monomers). These were identified as transferases D, C and A by their elution positions from CM-cellulose and their specific activities towards a variety of substrates. Hybridization, immunotitration and peptide 'mapping' experiments demonstrated that transferases D, C and A comprise Yb2Yb2, Yb1Yb2 and Yb1Yb1 subunits.

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Year:  1983        PMID: 6615452      PMCID: PMC1152177          DOI: 10.1042/bj2130625

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  23 in total

1.  Glutathione S-transferase AA from rat liver.

Authors:  W H Habig; M J Pabst; W B Jakoby
Journal:  Arch Biochem Biophys       Date:  1976-08       Impact factor: 4.013

2.  Purification of glutathione S-transferases from human liver by glutathione-affinity chromatography.

Authors:  P C Simons; D L Vander Jagt
Journal:  Anal Biochem       Date:  1977-10       Impact factor: 3.365

3.  Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.

Authors:  W H Habig; M J Pabst; W B Jakoby
Journal:  J Biol Chem       Date:  1974-11-25       Impact factor: 5.157

4.  Mercapturic acid formation: the several glutathione transferases of rat liver.

Authors:  M J Pabst; W H Habig; W B Jakoby
Journal:  Biochem Biophys Res Commun       Date:  1973-06-19       Impact factor: 3.575

5.  Enzymatic conjugation of epoxides with glutathione.

Authors:  T A Fjellstedt; R H Allen; B K Duncan; W B Jakoby
Journal:  J Biol Chem       Date:  1973-05-25       Impact factor: 5.157

6.  The amino acid sequence of Pseudomonas fluorescens azurin.

Authors:  R P Ambler; L H Brown
Journal:  Biochem J       Date:  1967-09       Impact factor: 3.857

7.  Ligandin, the glutathione S-transferases, and chemically induced hepatocarcinogenesis: a review.

Authors:  G J Smith; V S Ohl; G Litwack
Journal:  Cancer Res       Date:  1977-01       Impact factor: 12.701

8.  Ligandin heterogeneity : evidence that the two non-identical subunits are the monomers of two distinct proteins.

Authors:  N M Bass; R E Kirsch; S A Tuff; I Marks; S J Saunders
Journal:  Biochim Biophys Acta       Date:  1977-05-27

9.  Binding of nonsubstrate ligands to the glutathione S-transferases.

Authors:  J N Ketley; W H Habig; W B Jakoby
Journal:  J Biol Chem       Date:  1975-11-25       Impact factor: 5.157

10.  The reaction of aralkyl sulphate esters with glutathione catalysed by rat liver preparations.

Authors:  B Gillham
Journal:  Biochem J       Date:  1971-02       Impact factor: 3.857

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  19 in total

1.  Cytosolic glutathione transferases from rat liver. Primary structure of class alpha glutathione transferase 8-8 and characterization of low-abundance class Mu glutathione transferases.

Authors:  P Alin; H Jensson; E Cederlund; H Jörnvall; B Mannervik
Journal:  Biochem J       Date:  1989-07-15       Impact factor: 3.857

2.  Use of immuno-blot techniques to discriminate between the glutathione S-transferase Yf, Yk, Ya, Yn/Yb and Yc subunits and to study their distribution in extrahepatic tissues. Evidence for three immunochemically distinct groups of transferase in the rat.

Authors:  J D Hayes; T J Mantle
Journal:  Biochem J       Date:  1986-02-01       Impact factor: 3.857

3.  Purification and physical characterization of glutathione S-transferase K. Differential use of S-hexylglutathione and glutathione affinity matrices to isolate a novel glutathione S-transferase from rat liver.

Authors:  J D Hayes
Journal:  Biochem J       Date:  1986-02-01       Impact factor: 3.857

4.  Purification, induction, and distribution of placental glutathione transferase: a new marker enzyme for preneoplastic cells in the rat chemical hepatocarcinogenesis.

Authors:  K Satoh; A Kitahara; Y Soma; Y Inaba; I Hatayama; K Sato
Journal:  Proc Natl Acad Sci U S A       Date:  1985-06       Impact factor: 11.205

5.  Differential tissue expression of the glutathione transferase multigene family.

Authors:  S E Pemble; J B Taylor; R K Craig; B Ketterer
Journal:  Biochem J       Date:  1986-09-01       Impact factor: 3.857

6.  Rat lung glutathione S-transferases. Evidence for two distinct types of 22000-Mr subunits.

Authors:  S V Singh; C A Partridge; Y C Awasthi
Journal:  Biochem J       Date:  1984-08-01       Impact factor: 3.857

7.  Preferential over-expression of the class alpha rat Ya2 glutathione S-transferase subunit in livers bearing aflatoxin-induced pre-neoplastic nodules. Comparison of the primary structures of Ya1 and Ya2 with cloned class alpha glutathione S-transferase cDNA sequences.

Authors:  J D Hayes; L A Kerr; D J Harrison; A D Cronshaw; A G Ross; G E Neal
Journal:  Biochem J       Date:  1990-06-01       Impact factor: 3.857

8.  Ethoxyquin-induced resistance to aflatoxin B1 in the rat is associated with the expression of a novel alpha-class glutathione S-transferase subunit, Yc2, which possesses high catalytic activity for aflatoxin B1-8,9-epoxide.

Authors:  J D Hayes; D J Judah; L I McLellan; L A Kerr; S D Peacock; G E Neal
Journal:  Biochem J       Date:  1991-10-15       Impact factor: 3.857

9.  Expression of the placental form of glutathione S-transferase in pediatric gliomas.

Authors:  A Hara; N Sakai; H Yamada; S Niikawa; N Yoshimi; H Mori; K Shimokawa
Journal:  Childs Nerv Syst       Date:  1993-06       Impact factor: 1.475

10.  Evidence for two forms of ligandin (YaYa dimers of glutathione S-transferase) in rat liver and kidney.

Authors:  D Sheehan; T J Mantle
Journal:  Biochem J       Date:  1984-03-15       Impact factor: 3.857

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