Literature DB >> 6738510

Safety of fenbendazole use in cattle.

R K Muser, J W Paul.   

Abstract

Fenbendazole (Panacur: Hoechst) has a low degree of toxicity, teratogenicity and adverse effects on the reproductive tract, and a high degree of safety in experimental animals. Acute, subacute and long-term toxicity trials in cattle given fenbendazole at dosages of up to 2 g/kg revealed no adverse effects. Studies of teratogenicity, effects on fertility, compatibility with other drugs, and safety for animal handlers had similarly negative results.

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Year:  1984        PMID: 6738510

Source DB:  PubMed          Journal:  Mod Vet Pract        ISSN: 0362-8140


  4 in total

1.  Effects of Maternal Fenbendazole on Litter Size, Survival Rate, and Weaning Weight in C57BL/6J Mice.

Authors:  Kristina L Hicks; Elysia Roche; James D Wilkerson; Krista E Lindstrom
Journal:  J Am Assoc Lab Anim Sci       Date:  2021-11-09       Impact factor: 1.232

2.  Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways.

Authors:  Nilambra Dogra; Ashok Kumar; Tapas Mukhopadhyay
Journal:  Sci Rep       Date:  2018-08-09       Impact factor: 4.379

3.  Optimization and Pharmacokinetic Evaluation of Synergistic Fenbendazole and Rapamycin Co-Encapsulated in Methoxy Poly(Ethylene Glycol)-b-Poly(Caprolactone) Polymeric Micelles.

Authors:  Hee Ji Shin; Min Jeong Jo; Ik Sup Jin; Chun-Woong Park; Jin-Seok Kim; Dae Hwan Shin
Journal:  Int J Nanomedicine       Date:  2021-07-16

4.  The Benzimidazole-Based Anthelmintic Parbendazole: A Repurposed Drug Candidate That Synergizes with Gemcitabine in Pancreatic Cancer.

Authors:  Rosalba Florio; Serena Veschi; Viviana di Giacomo; Sara Pagotto; Simone Carradori; Fabio Verginelli; Roberto Cirilli; Adriano Casulli; Antonino Grassadonia; Nicola Tinari; Amelia Cataldi; Rosa Amoroso; Alessandro Cama; Laura De Lellis
Journal:  Cancers (Basel)       Date:  2019-12-17       Impact factor: 6.639

  4 in total

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