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Literature DB >> 6728031

Use of light for footprinting DNA in vivo.

Abstract

A new ' photofootprinting ' technique, which uses light to detect protein-DNA contacts as well as changes in the structure of DNA at the base pair level, has been developed and used to detect contacts between lac repressor and the lac operator in Escherichia coli cells.

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Year: 1984 PMID： 6728031 DOI： 10.1038/309682a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

46 in total

1. Poly(dA.dT) sequences exist as rigid DNA structures in nucleosome-free yeast promoters in vivo.

Authors: B Suter; G Schnappauf; F Thoma
Journal: Nucleic Acids Res Date: 2000-11-01 Impact factor: 16.971

2. Chromatin fine structure profiles for a developmentally regulated gene: reorganization of the lysozyme locus before trans-activator binding and gene expression.

Authors: J Kontaraki; H H Chen; A Riggs; C Bonifer
Journal: Genes Dev Date: 2000-08-15 Impact factor: 11.361

3. Transient XylR binding to the UAS of the Pseudomonas putida sigma54 promoter Pu revealed with high intensity UV footprinting in vivo.

Authors: Marc Valls; Víctor de Lorenzo
Journal: Nucleic Acids Res Date: 2003-12-01 Impact factor: 16.971

Use of light for footprinting DNA in vivo.

1. Poly(dA.dT) sequences exist as rigid DNA structures in nucleosome-free yeast promoters in vivo.

2. Chromatin fine structure profiles for a developmentally regulated gene: reorganization of the lysozyme locus before trans-activator binding and gene expression.

3. Transient XylR binding to the UAS of the Pseudomonas putida sigma54 promoter Pu revealed with high intensity UV footprinting in vivo.

4. Photofootprinting of DNA triplexes.

5. Micrococcal nuclease as a probe for bound and distorted DNA in lac transcription and repression complexes.

6. High resolution psoralen mapping reveals an altered DNA helical structure in the SV40 regulatory region.

7. Effects of DNA looping on pyrimidine dimer formation.

8. Thymine dimerization in DNA is an ultrafast photoreaction.

9. Origin of the heterogeneous distribution of the yield of guanyl radical in UV laser photolyzed DNA.

10. Thymine photodimer formation in DNA hairpins. Unusual conformations favor (6 - 4) vs. (2 + 2) adducts.