Literature DB >> 6726890

Analysis of T antigen and viral DNA in mouse cells transformed by K virus, a nononcogenic murine papovavirus.

T Kanda, K K Takemoto.   

Abstract

A tumorigenic line of mouse cells transformed by the nononcogenic murine K papovavirus was established and characterized. Tumor-bearing animals produced antibody specific for K virus-transformed cells; the K virus T antiserum did not react with polyomavirus-transformed cells. Immunoprecipitation of the T antigen in the transformed cells revealed large T antigen (molecular weight 84,000). About 10 to 15 copies of K virus DNA were found to be integrated in the cellular DNA.

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Year:  1984        PMID： 6726890      PMCID： PMC255761          DOI： 10.1128/JVI.50.3.954-956.1984

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  11 in total

1.  Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A.

Authors:  S W Kessler
Journal:  J Immunol       Date:  1975-12       Impact factor: 5.422

2.  Characterization of the genome of the murine papovavirus K.

Authors:  M F Law; K K Takemoto; P M Howley
Journal:  J Virol       Date:  1979-04       Impact factor: 5.103

3.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

4.  A general method for isolation of high molecular weight DNA from eukaryotes.

Authors:  N Blin; D W Stafford
Journal:  Nucleic Acids Res       Date:  1976-09       Impact factor: 16.971

5.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

6.  A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

Authors:  W M Bonner; R A Laskey
Journal:  Eur J Biochem       Date:  1974-07-01

7.  Transformation of mouse cells by K-papovavirus.

Authors:  K K Takemoto; P Fabisch
Journal:  Virology       Date:  1970-01       Impact factor: 3.616

8.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

9.  Characterization of K virus and its comparison with polyoma virus.

Authors:  S B Bond; P M Howley; K K Takemoto
Journal:  J Virol       Date:  1978-10       Impact factor: 5.103

10.  Pathogenesis of K virus infection in mice.

Authors:  J E Greenlee
Journal:  Prog Clin Biol Res       Date:  1983
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  1 in total

1.  Interaction of K papovavirus with hamster cells: transformation of glial cells in vitro but failure of the virus to produce central nervous system tumors in vivo.

Authors:  J E Greenlee; M F Law
Journal:  Arch Virol       Date:  1985       Impact factor: 2.574
  1 in total

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