| Literature DB >> 6724309 |
C J Lammi-Keefe, P B Swan, P V Hegarty.
Abstract
The activities of total superoxide dismutase (SOD) and the manganese (Mn SOD) and copper-zinc (Cu-Zn SOD) forms were determined in the supernatant fraction of heart, liver and six skeletal muscles from rats during aging. Total SOD activity increased in most muscles between 3 and 23 months of age. There was no change in activity in liver between 3 and 19 months of age. The increase in total activity in heart was due to increased Mn SOD activity, whereas increases in skeletal muscles were due to Cu-Zn SOD or to both Cu-Zn and Mn SOD. The nutritional implications during aging are discussed.Entities:
Mesh：
Substances：
Year: 1984 PMID： 6724309 DOI： 10.1159/000212623
Source DB: PubMed Journal: Gerontology ISSN： 0304-324X Impact factor: 5.140