| Literature DB >> 6716255 |
E Miyamoto, S Odashima, I Kitagawa, A Tsuji.
Abstract
The stability of ginsenosides (Rb1, Rb2, and Rg1) in aqueous solutions of varying pH was studied kinetically at 37 degrees C and an ionic strength of 0.15, using reverse-phase high-performance liquid chromatography. Degradation readily occurred by a proton-catalyzed reaction, the half-lives being only approximately 30 min at pH 1. However, under neutral intestinal pH conditions, the degradation was almost negligible throughout the experimental period (approximately 40 h).Entities:
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Year: 1984 PMID： 6716255 DOI： 10.1002/jps.2600730334
Source DB: PubMed Journal: J Pharm Sci ISSN： 0022-3549 Impact factor: 3.534