Literature DB >> 6716212

Encephalitis in mice with congenital ocular toxoplasmosis.

D I Graham, J Hay, W M Hutchison, J C Siim.   

Abstract

The brains of mice with congenital ocular toxoplasmosis were examined histologically. Toxoplasma tissue cysts and a subacute/chronic meningo-encephalitis were present in the brains of all infected mice. The findings were very similar to those seen in human congenital toxoplasmosis. The murine model of congenital toxoplasmic encephalitis described in this paper will be valuable in the study of the pathogenesis, natural history and treatment of this condition.

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Year:  1984        PMID： 6716212     DOI： 10.1002/path.1711420405

Source DB:  PubMed          Journal:  J Pathol        ISSN： 0022-3417            Impact factor:   7.996


  7 in total

1.  The immunocytochemical demonstration of Toxoplasma antigen in the brains of congenitally infected mice.

Authors:  J Hay; D I Graham; G N Dutton; S Logan
Journal:  Z Parasitenkd       Date:  1986

2.  Effect of Toxoplasma gondii infection kinetics on trophoblast cell population in Calomys callosus, a model of congenital toxoplasmosis.

Authors:  E A V Ferro; D A O Silva; E Bevilacqua; J R Mineo
Journal:  Infect Immun       Date:  2002-12       Impact factor: 3.441

3.  An electron microscope and immunohistochemical study of the intracellular location of Toxoplasma tissue cysts within the brains of mice with congenital toxoplasmosis.

Authors:  T A Sims; J Hay; I C Talbot
Journal:  Br J Exp Pathol       Date:  1989-06

4.  The influence of congenital Toxoplasma infection on the spontaneous running activity of mice.

Authors:  J Hay; P P Aitken; M A Arnott
Journal:  Z Parasitenkd       Date:  1985

5.  Pathological changes in the brains of mice infected with Toxoplasma gondii: a histological, immunocytochemical and ultrastructural study.

Authors:  D J Ferguson; D I Graham; W M Hutchison
Journal:  Int J Exp Pathol       Date:  1991-08       Impact factor: 1.925

6.  Clinicopathological features of a congenital murine model of ocular toxoplasmosis.

Authors:  G N Dutton; J Hay; D M Hair; J Ralston
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1986       Impact factor: 3.117

7.  Rat model of congenital toxoplasmosis: rate of transmission of three Toxoplasma gondii strains to fetuses and protective effect of a chronic infection.

Authors:  L Zenner; F Darcy; M F Cesbron-Delauw; A Capron
Journal:  Infect Immun       Date:  1993-01       Impact factor: 3.441
  7 in total

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