Literature DB >> 6673077

Neurotensin inhibits meal-stimulated gastric acid secretion in man.

P Skov Olsen, J Holst Pedersen, P Kirkegaard, F Stadil, J Fahrenkrug, J Christiansen.   

Abstract

The effect of physiological doses of exogenous neurotensin on meal-stimulated gastric acid secretion and serum gastrin concentration was investigated in six healthy subjects. Acid secretion was reduced by 32% during intravenous infusion of neurotensin, the plasma neurotensin concentration being within physiological range. Serum gastrin concentration was unchanged during infusion of neurotensin. The results strongly suggest that neurotensin participates in the regulation of gastric acid secretion and support the theory that neurotensin may play a role in the intestinal phase of gastric acid secretion in man.

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Year:  1983        PMID： 6673077     DOI： 10.3109/00365528309181843

Source DB:  PubMed          Journal:  Scand J Gastroenterol        ISSN： 0036-5521            Impact factor:   2.423


  6 in total

1.  Changes of Gastric Secretion after Bolus and Slow Intravenous Administration of Bombesin and Neurotensin.

Authors:  Konstantinos Tsalis; Orestis Ioannidis; Chrysovalantis Mariorakis; Panagiotis Christidis; Lydia Loutzidou; Ioannis Mantzoros; Efstathios Kotidis; Manousos George Pramateftakis; Nikolaos Ouzounidis; Stamatios Aggelopoulos
Journal:  Maedica (Bucur)       Date:  2021-12

2.  The role of neurotensin in human gallbladder motility.

Authors:  J P Walker; T Khalil; I Wiener; C J Fagan; C M Townsend; G H Greeley; J C Thompson
Journal:  Ann Surg       Date:  1985-06       Impact factor: 12.969

3.  Neurotensin induced inhibition of gastric acid secretion in duodenal ulcer patients before and after parietal cell vagotomy.

Authors:  P S Olsen; J H Pedersen; P Kirkegaard; H Been; F Stadil; J Fahrenkrug; J Christiansen
Journal:  Gut       Date:  1984-05       Impact factor: 23.059

4.  Regulation of gastric acid secretion by neurotensin in man. Evidence against a hormonal role.

Authors:  M H Mogard; V Maxwell; B Sytnik; J H Walsh
Journal:  J Clin Invest       Date:  1987-10       Impact factor: 14.808

5.  Role of proneurotensin as marker of paediatric coeliac disease.

Authors:  C Montén; Å Torinsson Naluai; D Agardh
Journal:  Clin Exp Immunol       Date:  2016-10-07       Impact factor: 4.330

6.  Neurotensin prevents intestinal mucosal hypoplasia in rats fed an elemental diet.

Authors:  B M Evers; M Izukura; C M Townsend; T Uchida; J C Thompson
Journal:  Dig Dis Sci       Date:  1992-03       Impact factor: 3.199
  6 in total

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