Literature DB >> 6712597

Cystatin. Amino acid sequence and possible secondary structure.

C Schwabe, A Anastasi, H Crow, J K McDonald, A J Barrett.   

Abstract

The amino acid sequence of cystatin, the protein from chicken egg-white that is a tight-binding inhibitor of many cysteine proteinases, is reported. Cystatin is composed of 116 amino acid residues, and the Mr is calculated to be 13 143. No striking similarity to any other known sequence has been detected. The results of computer analysis of the sequence and c.d. spectrometry indicate that the secondary structure includes relatively little alpha-helix (about 20%) and that the remainder is mainly beta-structure.

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Year:  1984        PMID: 6712597      PMCID: PMC1153285          DOI: 10.1042/bj2170813

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  13 in total

1.  Conformational properties of amino acid residues in globular proteins.

Authors:  B Robson; E Suzuki
Journal:  J Mol Biol       Date:  1976-11-05       Impact factor: 5.469

2.  Conservation of chain reversal regions in proteins.

Authors:  P Y Chou; G D Fasman
Journal:  Biophys J       Date:  1979-06       Impact factor: 4.033

3.  Prediction of beta-turns.

Authors:  P Y Chou; G D Fasman
Journal:  Biophys J       Date:  1979-06       Impact factor: 4.033

4.  Fluorescamine: a reagent for assay of amino acids, peptides, proteins, and primary amines in the picomole range.

Authors:  S Udenfriend; S Stein; P Böhlen; W Dairman; W Leimgruber; M Weigele
Journal:  Science       Date:  1972-11-24       Impact factor: 47.728

5.  The complete amino-acid sequence of human -lactalbumin.

Authors:  J B Findlay; K Brew
Journal:  Eur J Biochem       Date:  1972-05

6.  Triplet information in helix prediction applied to the analysis of super-secondary structures.

Authors:  K Nagano
Journal:  J Mol Biol       Date:  1977-01-15       Impact factor: 5.469

7.  Automated amino acid sequence of small peptides utilizing Polybrene.

Authors:  D G Klapper; C E Wilde; J D Capra
Journal:  Anal Biochem       Date:  1978-03       Impact factor: 3.365

Review 8.  Protein inhibitors of proteinases.

Authors:  M Laskowski; I Kato
Journal:  Annu Rev Biochem       Date:  1980       Impact factor: 23.643

9.  Characterization of an inducible amidase from Pseudomonas acidovorans AE1.

Authors:  J Alt; E Heymann; K Krisch
Journal:  Eur J Biochem       Date:  1975-05-06

10.  Secondary structures of proteins from the 30S subunit of the Escherichia coli ribosome.

Authors:  M Dzionara; S M Robinson; B Wittmann-Liebold
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1977-08
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  15 in total

1.  A constitutive cystatin-encoding gene from barley (Icy) responds differentially to abiotic stimuli.

Authors:  K Gaddour; J Vicente-Carbajosa; P Lara; I Isabel-Lamoneda; I Díaz; P Carbonero
Journal:  Plant Mol Biol       Date:  2001-03       Impact factor: 4.076

2.  Evolution of proteins of the cystatin superfamily.

Authors:  N D Rawlings; A J Barrett
Journal:  J Mol Evol       Date:  1990-01       Impact factor: 2.395

3.  Prevention of amyloid fibril formation of amyloidogenic chicken cystatin by site-specific glycosylation in yeast.

Authors:  Jianwei He; Youtao Song; Nobuhiro Ueyama; Akira Saito; Hiroyuki Azakami; Akio Kato
Journal:  Protein Sci       Date:  2006-02       Impact factor: 6.725

4.  Internally repeated sequences in ras gene products.

Authors:  T Hiwasa
Journal:  Biochem J       Date:  1988-09-01       Impact factor: 3.857

5.  Arrangement of the disulphide bridges in human low-Mr kininogen.

Authors:  J Kellermann; C Thelen; F Lottspeich; A Henschen; R Vogel; W Müller-Esterl
Journal:  Biochem J       Date:  1987-10-01       Impact factor: 3.857

6.  Cystatin-like cysteine proteinase inhibitors from human liver.

Authors:  G D Green; A A Kembhavi; M E Davies; A J Barrett
Journal:  Biochem J       Date:  1984-03-15       Impact factor: 3.857

7.  Inhibition of cysteine proteinases and dipeptidyl peptidase I by egg-white cystatin.

Authors:  M J Nicklin; A J Barrett
Journal:  Biochem J       Date:  1984-10-01       Impact factor: 3.857

8.  Human low-Mr kininogen contains three copies of a cystatin sequence that are divergent in structure and in inhibitory activity for cysteine proteinases.

Authors:  G Salvesen; C Parkes; M Abrahamson; A Grubb; A J Barrett
Journal:  Biochem J       Date:  1986-03-01       Impact factor: 3.857

9.  Characterization by rapid-kinetic and equilibrium methods of the interaction between N-terminally truncated forms of chicken cystatin and the cysteine proteinases papain and actinidin.

Authors:  P Lindahl; M Nycander; K Ylinenjärvi; E Pol; I Björk
Journal:  Biochem J       Date:  1992-08-15       Impact factor: 3.857

10.  Amyloid fibrils in hereditary cerebral hemorrhage with amyloidosis of Icelandic type is a variant of gamma-trace basic protein (cystatin C).

Authors:  J Ghiso; O Jensson; B Frangione
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

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