Literature DB >> 6710263

Biodegradable serum albumin polymers for the sustained release of virus antigens in vaccines. A preliminary report.

J B Dewar, D A Hendry, J F Newman.   

Abstract

In an experimental vaccine, virus particles were chemically cross-linked into rabbit serum albumin beads. This vaccine was injected into rabbits without adverse reactions and the humoral antibody levels achieved were comparable to those obtained using virus emulsified in Freund's adjuvant. The antibodies produced were capable of neutralizing virus infectivity.

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Year:  1984        PMID: 6710263

Source DB:  PubMed          Journal:  S Afr Med J


  2 in total

1.  Enhanced tumor metastases upon drug delivery in cross-linked albumin beads.

Authors:  M P Moyer; A Armstrong; J Parra; D Escobar
Journal:  Clin Exp Metastasis       Date:  1986 Jan-Mar       Impact factor: 5.150

Review 2.  Immunopotentiation and delivery systems for antigens for single-step immunization: recent trends and progress.

Authors:  M Z Khan; J P Opdebeeck; I G Tucker
Journal:  Pharm Res       Date:  1994-01       Impact factor: 4.200

  2 in total

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