Literature DB >> 6709041

Alternative transcription and two modes of splicing results in two myosin light chains from one gene.

Y Nabeshima, Y Fujii-Kuriyama, M Muramatsu, K Ogata.   

Abstract

Chicken skeletal muscle myosin alkali light chains are encoded by a single gene of size 18 kilobases (kb). This gene has two transcription initiation sites from which 17.5- and 8-kb precursor RNAs are transcribed. These RNAs are processed by different modes of splicing to form mRNAs encoding distinct light-chain (LC1 and LC3) proteins.

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Year:  1984        PMID： 6709041     DOI： 10.1038/308333a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  102 in total

1.  Mutually exclusive exon splicing of the cardiac calcium channel alpha 1 subunit gene generates developmentally regulated isoforms in the rat heart.

Authors:  R J Diebold; W J Koch; P T Ellinor; J J Wang; M Muthuchamy; D F Wieczorek; A Schwartz
Journal:  Proc Natl Acad Sci U S A       Date:  1992-02-15       Impact factor: 11.205

2.  Probing myosin light chain 1 structure with monoclonal antibodies.

Authors:  B Cornillon; A M Cathiard; P Eldin; M Anoal; R Cardinaud; J P Liautard; M Le Cunff; D Mornet; F Pons; J Leger
Journal:  J Muscle Res Cell Motil       Date:  1992-06       Impact factor: 2.698

3.  A highly conserved enhancer downstream of the human MLC1/3 locus is a target for multiple myogenic determination factors.

Authors:  N Rosenthal; E B Berglund; B M Wentworth; M Donoghue; B Winter; E Bober; T Braun; H H Arnold
Journal:  Nucleic Acids Res       Date:  1990-11-11       Impact factor: 16.971

Review 4.  Myosin light chains and troponin C: structural and evolutionary relationships revealed by amino acid sequence comparisons.

Authors:  J H Collins
Journal:  J Muscle Res Cell Motil       Date:  1991-02       Impact factor: 2.698

5.  The human embryonic myosin alkali light chain gene: use of alternative promoters and 3' non-coding regions.

Authors:  M Rotter; K Zimmerman; A Poustka; N Soussi-Yanicostas; A Starzinski-Powitz
Journal:  Nucleic Acids Res       Date:  1991-04-11       Impact factor: 16.971

6.  Evolution of EF-hand calcium-modulated proteins. I. Relationships based on amino acid sequences.

Authors:  N D Moncrief; R H Kretsinger; M Goodman
Journal:  J Mol Evol       Date:  1990-06       Impact factor: 2.395

7.  Differential expression of two distinct forms of mRNA encoding members of a dipeptidyl aminopeptidase family.

Authors:  K Wada; N Yokotani; C Hunter; K Doi; R J Wenthold; S Shimasaki
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-01       Impact factor: 11.205

8.  Antisense suppression of skeletal muscle myosin light chain-1 biosynthesis impairs myofibrillogenesis in cultured myotubes.

Authors:  R Nawrotzki; D A Fischman; T Mikawa
Journal:  J Muscle Res Cell Motil       Date:  1995-02       Impact factor: 2.698

9.  Paired MyoD-binding sites regulate myosin light chain gene expression.

Authors:  B M Wentworth; M Donoghue; J C Engert; E B Berglund; N Rosenthal
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-15       Impact factor: 11.205

10.  Cell proliferation-associated expression of a recently evolved isozyme of triosephosphate isomerase.

Authors:  R S Decker; H W Mohrenweiser
Journal:  Biochem Genet       Date:  1985-04       Impact factor: 1.890
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