Literature DB >> 6705132

The efficiency of protective gloves used in the handling of cytotoxic drugs.

M L Slevin, L M Ang, A Johnston, P Turner.   

Abstract

A range of clinical and industrial gloves have been evaluated to determine their ability to exclude penetration by cytotoxic drugs. Radiolabelled cyclophosphamide, methotrexate, daunomycin, cytosine arabinoside, and vincristine sulphate were studied in an equilibrium dialysis system in which the glove material was used as the dialysis membrane. The thicker gloves were the most effective, but very little drug crossed any of the gloves tested under laboratory conditions. Further studies to evaluate gloves in conditions of clinical use are now needed.

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Year:  1984        PMID: 6705132     DOI: 10.1007/bf00256536

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN: 0344-5704            Impact factor:   3.333


  5 in total

1.  Protective capacity of gloves used for handling of nitrogen mustard.

Authors:  K Thomsen; H I Mikkelsen
Journal:  Contact Dermatitis       Date:  1975-08       Impact factor: 6.600

2.  Mutagenicity in urine of nurses handling cytostatic drugs.

Authors:  K Falck; P Gröhn; M Sorsa; H Vainio; E Heinonen; L R Holsti
Journal:  Lancet       Date:  1979-06-09       Impact factor: 79.321

3.  Handling of injectable antineoplastic agents.

Authors:  R S Knowles; J E Virden
Journal:  Br Med J       Date:  1980-08-30

4.  Acute myelogenous leukemia in patients receiving chlorambucil as long-term adjuvant chemotherapy for stage II breast cancer.

Authors:  H J Lerner
Journal:  Cancer Treat Rep       Date:  1978-08

5.  Risk of handling injectable antineoplastic agents.

Authors:  R W Anderson; W H Puckett; W J Dana; T V Nguyen; J C Theiss; T S Matney
Journal:  Am J Hosp Pharm       Date:  1982-11
  5 in total
  5 in total

Review 1.  Drugs hazardous to healthcare workers. Evaluation of methods for monitoring occupational exposure to cytostatic drugs.

Authors:  P J Sessink; R P Bos
Journal:  Drug Saf       Date:  1999-04       Impact factor: 5.606

Review 2.  The risks of handling cytotoxic drugs. II. Recommendations for working with cytotoxic drugs.

Authors:  G P Kaijser; W J Underberg; J H Beijnen
Journal:  Pharm Weekbl Sci       Date:  1990-12-14

3.  Biological monitoring of cyclophosphamide and ifosfamide in urine of hospital personnel occupationally exposed to cytostatic drugs.

Authors:  A S Ensslin; Y Stoll; A Pethran; A Pfaller; H Römmelt; G Fruhmann
Journal:  Occup Environ Med       Date:  1994-04       Impact factor: 4.402

4.  Detection of contamination with antineoplastic agents in a hospital pharmacy department.

Authors:  P J Sessink; R B Anzion; P H Van den Broek; R P Bos
Journal:  Pharm Weekbl Sci       Date:  1992-02-21

5.  Biological and environmental monitoring of occupational exposure of pharmaceutical plant workers to methotrexate.

Authors:  P J Sessink; N S Friemèl; R B Anzion; R P Bos
Journal:  Int Arch Occup Environ Health       Date:  1994       Impact factor: 3.015

  5 in total

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