Literature DB >> 669729

Transforming activities of trichloroethylene and proposed industrial alternatives.

P J Price, C M Hassett, J I Mansfield.   

Abstract

Three chlorinated hydrocarbons, proposed or already in use as industrial substitutes for the hydrocarbon trichloroethylene, were tested for in vitro transforming potential in a Fischer rat embryo cell system (F1706), which previously has been shown to be sensitive to transformation by chemical carcinogens. Trichloroethylene and the three substitutes (1, 1, 1 trichloroethane, tetrachloroethylene and methylene chloride) all were found to induce transformation, the three substitutes being equal or more efficient transforming agents.

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Year:  1978        PMID： 669729     DOI： 10.1007/BF02616038

Source DB:  PubMed          Journal:  In Vitro        ISSN： 0073-5655


  2 in total

1.  Efficient detection of soft agar grown colonies using a tetrazolium salt.

Authors:  W I Schaeffer; K Friend
Journal:  Cancer Lett       Date:  1976-05       Impact factor: 8.679

2.  I. In vitrol transformation of rat embryo cells: correlations with the known tumorigenic activities of chemicals in rodents.

Authors:  A E Freeman; H J Igel; P J Price
Journal:  In Vitro       Date:  1975 Mar-Apr
  2 in total
  2 in total

1.  Interactions of trichloroethylene with DNA in vitro and with RNA and DNA of various mouse tissues in vivo.

Authors:  K Bergman
Journal:  Arch Toxicol       Date:  1983-11       Impact factor: 5.153

2.  Identification of potential carcinogens in technical grade 1,1,1-trichloroethane.

Authors:  D Henschler; D Reichert; M Metzler
Journal:  Int Arch Occup Environ Health       Date:  1980       Impact factor: 3.015
  2 in total

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