| Literature DB >> 6697225 |
G Pasinetti, S Govoni, S di Giovine, P F Spano, M Trabucchi.
Abstract
The basal release of Met-enkephalin immunoreactive material (ME-IR) from rat striatal slices is doubled by the in vitro addition of 5 X 10(-5) M dopamine. The K+ evoked release of ME-IR is also slightly enhanced by exposing the slices to dopamine. The effect of dopamine is shared by apomorphine but not by norepinephrine. Neuroleptics do not alter the basal or the K+-stimulated ME-IR release but reverse the dopamine-induced increase. These results suggest that the stimulation of dopamine receptors may influence the enkephalin release within striatum.Entities:
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Year: 1984 PMID： 6697225 DOI： 10.1016/0006-8993(84)91244-7
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252