| Literature DB >> 6693175 |
Abstract
The in vitro immune responsiveness of lymphocytes from Brugia pahangi-infected jirds was examined after serial administration of cyclophosphamide (20 mg/kg). Cyclophosphamide had no effect on parasite burdens, anti-B. pahangi antibody titers, or suppressed spleen cell reactivity to B. pahangi antigens. Cyclophosphamide restored cellular responsiveness to the mitogens phytohemagglutinin, concanavalin A, and pokeweed mitogen.Entities:
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Year: 1984 PMID: 6693175 PMCID: PMC264365 DOI: 10.1128/iai.43.2.753-755.1984
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441