Literature DB >> 6693175

Effect of cyclophosphamide on the immune responsiveness of jirds infected with Brugia pahangi.

S P Katz, P J Lammie.   

Abstract

The in vitro immune responsiveness of lymphocytes from Brugia pahangi-infected jirds was examined after serial administration of cyclophosphamide (20 mg/kg). Cyclophosphamide had no effect on parasite burdens, anti-B. pahangi antibody titers, or suppressed spleen cell reactivity to B. pahangi antigens. Cyclophosphamide restored cellular responsiveness to the mitogens phytohemagglutinin, concanavalin A, and pokeweed mitogen.

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Year:  1984        PMID: 6693175      PMCID: PMC264365          DOI: 10.1128/iai.43.2.753-755.1984

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  16 in total

1.  Adoptive suppression of granuloma formation by T lymphocytes and by lymphoid cells sensitive to cyclophosphamide.

Authors:  D G Colley; F A Lewis; C W Todd
Journal:  Cell Immunol       Date:  1979-08       Impact factor: 4.868

2.  Regulation of delayed-type hypersensitivity reactions by cyclophosphamide-sensitive T cells.

Authors:  A Schwartz; P W Askenase; R K Gershon
Journal:  J Immunol       Date:  1978-10       Impact factor: 5.422

3.  Specific cellular immune unresponsiveness in human filariasis.

Authors:  E A Ottesen; P F Weller; L Heck
Journal:  Immunology       Date:  1977-09       Impact factor: 7.397

4.  Filarial antibodies and eosinophilia in human subjects in an endemic area.

Authors:  M M Wong; M F Guest
Journal:  Trans R Soc Trop Med Hyg       Date:  1969       Impact factor: 2.184

5.  Immunologic suppression after oral administration of antigen. I. Specific suppressor cells formed in rat Peyer's patches after oral administration of sheep erythrocytes and their systemic migration.

Authors:  J A Mattingly; B H Waksman
Journal:  J Immunol       Date:  1978-11       Impact factor: 5.422

6.  Antigen-specific suppressor cells and suppressor factors in human filariasis with Brugia malayi.

Authors:  W F Piessens; S Ratiwayanto; S Tuti; J H Palmieri; P W Piessens; I Koiman; D T Dennis
Journal:  N Engl J Med       Date:  1980-04-10       Impact factor: 91.245

7.  Immune responses in human infections with Brugia malayi: specific cellular unresponsiveness to filarial antigens.

Authors:  W F Piessens; P B McGreevy; P W Piessens; M McGreevy; I Koiman; J S Saroso; D T Dennis
Journal:  J Clin Invest       Date:  1980-01       Impact factor: 14.808

8.  Non-specific suppression of antigen-induced lymphocyte blastogenesis in Onchocerca volvulus infection in man.

Authors:  B M Greene; M M Fanning; J J Ellner
Journal:  Clin Exp Immunol       Date:  1983-05       Impact factor: 4.330

9.  Specific allergic sensitsation to filarial antigens in tropical eosinophilia syndrome.

Authors:  E A Ottesen; F A Neva; R S Paranjape; S P Tripathy; K V Thiruvengadam; M A Beaven
Journal:  Lancet       Date:  1979-06-02       Impact factor: 79.321

10.  Augmentation of delayed-type hypersensitivity by doses of cyclophosphamide which do not affect antibody responses.

Authors:  P W Askenase; B J Hayden; R K Gershon
Journal:  J Exp Med       Date:  1975-03-01       Impact factor: 14.307

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  4 in total

1.  Effect of cyclophosphamide on the candidacidal activity of rabbit peritoneal macrophages.

Authors:  D Kotulová; M Zalkovicová; J Stefanovic
Journal:  Folia Microbiol (Praha)       Date:  1988       Impact factor: 2.099

2.  Evaluation of the immunosuppressive effect of cyclophosphamide and dexamethasone in mice with visceral toxocariasis.

Authors:  Luciana Farias da Costa de Avila; Juliana Santos Vieira da Fonseca; Gisele Ferreira Dutra; Paula de Lima Telmo; Ana Maria Wolkmer Azambuja Silva; Maria Elisabeth Aires Berne; Pedro Eduardo Almeida da Silva; Fabricio Rochedo Conceição; Carlos James Scaini
Journal:  Parasitol Res       Date:  2011-07-12       Impact factor: 2.289

3.  Immunoregulation in experimental filariasis. IV. Induction of non-specific suppression following in vitro exposure of spleen cells from infected jirds to Brugia pahangi antigen.

Authors:  P J Lammie; S P Katz
Journal:  Immunology       Date:  1984-06       Impact factor: 7.397

4.  Immunoregulation in experimental filariasis. III. Demonstration and characterization of antigen-specific suppressor cells in the spleen of Brugia pahangi-infected jirds.

Authors:  P J Lammie; S P Katz
Journal:  Immunology       Date:  1984-06       Impact factor: 7.397

  4 in total

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