Literature DB >> 6688788

The presence of peptide histidine-isoleucine in human, dog, guinea-pig and rat pancreas.

Y Yiangou, N D Christofides, J E Evans, S R Bloom.   

Abstract

Peptide histidine isoleucine-like immunoreactivity has been detected in the pancreas of man (10.3 +/- 2.6 pmol/g), dog (6.5 +/- 1.1 pmol/g), guinea-pig (5.8 +/- 0.9 pmol/g) and rat (0.7 +/- 0.1 pmol/g) using a specific radioimmunoassay. Chromatographic analysis of the pancreatic extracts by high performance liquid chromatography indicated that both guinea-pig and rat have a molecular form of the immunoreactivity which is distinct from the porcine intestinal peptide histidine-isoleucine.

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Year:  1983        PMID： 6688788     DOI： 10.1007/bf00250901

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


  10 in total

1.  Distribution of peptide histidine isoleucine in the mammalian respiratory tract and some aspects of its pharmacology.

Authors:  N D Christofides; Y Yiangou; P J Piper; M A Ghatei; M N Sheppard; K Tatemoto; J M Polak; S R Bloom
Journal:  Endocrinology       Date:  1984-11       Impact factor: 4.736

2.  Actions of a new peptide from porcine intestine (PHI) on pancreatic secretion in the rat and turkey.

Authors:  R Dimaline; G J Dockray
Journal:  Life Sci       Date:  1980-11-24       Impact factor: 5.037

3.  Radioimmunoassay and intramural distribution of PHI-IR in human intestine.

Authors:  N D Christofides; Y Yiangou; E Aarons; G L Ferri; K Tatemoto; J M Polak; S R Bloom
Journal:  Dig Dis Sci       Date:  1983-06       Impact factor: 3.199

4.  Ontogeny of PHI in the rat brain.

Authors:  N D Christofides; G P McGregor; P L Woodhams; Y Yiangou; E Aarons; K Tatemoto; S R Bloom
Journal:  Brain Res       Date:  1983-04-04       Impact factor: 3.252

5.  Interaction of a newly isolated intestinal polypeptide (PHI) with glucose and arginine to effect the secretion of insulin and glucagon.

Authors:  J Szecówka; K Tatemoto; V Mutt; S Efendić
Journal:  Life Sci       Date:  1980-02-11       Impact factor: 5.037

6.  Bombesin: action on gut hormones and calcium in man.

Authors:  M A Ghatei; R T Jung; J C Stevenson; C J Hillyard; T E Adrian; Y C Lee; N D Christofides; D L Sarson; K Mashiter; I MacIntyre; S R Bloom
Journal:  J Clin Endocrinol Metab       Date:  1982-05       Impact factor: 5.958

7.  The location of VIP in the pancreas of man and rat.

Authors:  A E Bishop; J M Polak; I C Green; M G Bryant; S R Bloom
Journal:  Diabetologia       Date:  1980-01       Impact factor: 10.122

8.  Regional distribution and concentration of pancreatic polypeptide in the human and canine pancreas.

Authors:  D J Gersell; R L Gingerich; M H Greider
Journal:  Diabetes       Date:  1979-01       Impact factor: 9.461

9.  Isolation and characterization of the intestinal peptide porcine PHI (PHI-27), a new member of the glucagon--secretin family.

Authors:  K Tatemoto; V Mutt
Journal:  Proc Natl Acad Sci U S A       Date:  1981-11       Impact factor: 11.205

10.  Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril.

Authors:  P J Fraker; J C Speck
Journal:  Biochem Biophys Res Commun       Date:  1978-02-28       Impact factor: 3.575
  10 in total
  1 in total

1.  Co-release of PHI and VIP in dog stomach by peripheral and central vagal stimulation.

Authors:  T Ohta; S Ito; A Ohga
Journal:  Br J Pharmacol       Date:  1990-06       Impact factor: 8.739
  1 in total

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