Literature DB >> 6687716

The nucleotide sequence of the cDNA coding for the human dihydrofolic acid reductase.

J N Masters, G Attardi.   

Abstract

The nucleotide sequence of the human dihydrofolic acid reductase (DHFR) reading frame has been derived from the analysis of human DHFR cDNA. This sequence and the corresponding amino acid sequence have been compared with those available for the enzyme and its coding segment from other organisms. There is an 89% nucleotide sequence homology between the human DHFR reading frame and the mouse coding sequence. Furthermore, amino acid-sequence homologies of 74%, 81% and 89% has been found between human DHFR and chicken, bovine and mouse DHFR, respectively.

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Year:  1983        PMID： 6687716     DOI： 10.1016/0378-1119(83)90147-6

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  18 in total

1.  Detection of point mutations in human DNA by analysis of RNA conformation polymorphism(s).

Authors:  P V Danenberg; T Horikoshi; M Volkenandt; K Danenberg; H J Lenz; L C Shea; A P Dicker; A Simoneau; P A Jones; J R Bertino
Journal:  Nucleic Acids Res       Date:  1992-02-11       Impact factor: 16.971

2.  Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene.

Authors:  D J Bzik; W B Li; T Horii; J Inselburg
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

3.  Pseudosecretion of Escherichia coli chloramphenicol acetyltransferase by Bacillus subtilis.

Authors:  S F Le Grice; R Gentz; W Bannwarth; H P Kocher
Journal:  J Bacteriol       Date:  1987-07       Impact factor: 3.490

4.  Nucleotide sequence of a functional cDNA for human thymidylate synthase.

Authors:  K Takeishi; S Kaneda; D Ayusawa; K Shimizu; O Gotoh; T Seno
Journal:  Nucleic Acids Res       Date:  1985-03-25       Impact factor: 16.971

5.  Characterization of transposon Tn5086, carrying the site-specifically inserted gene dhfrVII mediating trimethoprim resistance.

Authors:  L Sundström; G Swedberg; O Sköld
Journal:  J Bacteriol       Date:  1993-03       Impact factor: 3.490

6.  Phenotypic expression in Escherichia coli and nucleotide sequence of two Chinese hamster lung cell cDNAs encoding different dihydrofolate reductases.

Authors:  P W Melera; J P Davide; C A Hession; K W Scotto
Journal:  Mol Cell Biol       Date:  1984-01       Impact factor: 4.272

7.  Human dihydropteridine reductase: characterisation of a cDNA clone and its use in analysis of patients with dihydropteridine reductase deficiency.

Authors:  H H Dahl; W Hutchison; W McAdam; S Wake; F J Morgan; R G Cotton
Journal:  Nucleic Acids Res       Date:  1987-03-11       Impact factor: 16.971

8.  5' Nucleotide sequences influence serum-modulated expression of a human dihydrofolate reductase minigene.

Authors:  M E Goldsmith; C A Beckman; K H Cowan
Journal:  Mol Cell Biol       Date:  1986-03       Impact factor: 4.272

9.  Hodgkin's disease cell lines: a model for interleukin-1-independent accessory cell function.

Authors:  J L McKenzie; W Egner; V L Calder; D N Hart
Journal:  Immunology       Date:  1992-11       Impact factor: 7.397

10.  Human dihydrofolate reductase gene is located in chromosome 5 and is unlinked to the related pseudogenes.

Authors:  B J Maurer; P E Barker; J N Masters; F H Ruddle; G Attardi
Journal:  Proc Natl Acad Sci U S A       Date:  1984-03       Impact factor: 11.205
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