Literature DB >> 6685521

Plasma lipids in twins. Environmental and genetic influences.

J B Whitfield, N G Martin.   

Abstract

A study on 205 pairs of male and females twins, aged from 18 to 34 years. showed significant heritabilities for total and high density lipoprotein cholesterol and for triglycerides. Significant effects of shared environment were also found for total and HDL cholesterol, possibly to a greater extent in women than in men. Triglycerides showed greater variance in men but a model specifying different sized environmental and genetic parameters in the two sexes gave a good fit and indicated that the factors influencing plasma triglycerides are the same in men and women although the effects they produce are scaled differently.

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Year:  1983        PMID: 6685521     DOI: 10.1016/0021-9150(83)90044-8

Source DB:  PubMed          Journal:  Atherosclerosis        ISSN: 0021-9150            Impact factor:   5.162


  9 in total

1.  Human pedigree-based quantitative-trait-locus mapping: localization of two genes influencing HDL-cholesterol metabolism.

Authors:  L Almasy; J E Hixson; D L Rainwater; S Cole; J T Williams; M C Mahaney; J L VandeBerg; M P Stern; J W MacCluer; J Blangero
Journal:  Am J Hum Genet       Date:  1999-06       Impact factor: 11.025

2.  Evidence of linkage of HDL level variation to APOC3 in two samples with different ascertainment.

Authors:  France Gagnon; Gail P Jarvik; Arno G Motulsky; Samir S Deeb; John D Brunzell; Ellen M Wijsman
Journal:  Hum Genet       Date:  2003-08-29       Impact factor: 4.132

3.  Genome scan for quantitative trait loci influencing HDL levels: evidence for multilocus inheritance in familial combined hyperlipidemia.

Authors:  France Gagnon; Gail P Jarvik; Michael D Badzioch; Arno G Motulsky; John D Brunzell; Ellen M Wijsman
Journal:  Hum Genet       Date:  2005-06-16       Impact factor: 4.132

4.  Is family history an independent risk factor for stroke?

Authors:  M Kubota; A Yamaura; J Ono; T Itani; N Tachi; K Ueda; I Nagata; S Sugimoto
Journal:  J Neurol Neurosurg Psychiatry       Date:  1997-01       Impact factor: 10.154

5.  Genetic and environmental correlations among serum lipids and apolipoproteins in elderly twins reared together and apart.

Authors:  D A Heller; N L Pedersen; U de Faire; G E McClearn
Journal:  Am J Hum Genet       Date:  1994-12       Impact factor: 11.025

6.  Evidence of differential allelic effects between adolescents and adults for plasma high-density lipoprotein.

Authors:  Rita P S Middelberg; Andrew C Heath; Pamela A F Madden; Grant W Montgomery; Nicholas G Martin; John B Whitfield
Journal:  PLoS One       Date:  2012-04-18       Impact factor: 3.240

7.  Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.

Authors:  Rita P S Middelberg; Manuel A R Ferreira; Anjali K Henders; Andrew C Heath; Pamela A F Madden; Grant W Montgomery; Nicholas G Martin; John B Whitfield
Journal:  BMC Med Genet       Date:  2011-09-24       Impact factor: 2.103

8.  Heritability and Genome-Wide Association Study of Plasma Cholesterol in Chinese Adult Twins.

Authors:  Hui Liu; Weijing Wang; Caixia Zhang; Chunsheng Xu; Haiping Duan; Xiaocao Tian; Dongfeng Zhang
Journal:  Front Endocrinol (Lausanne)       Date:  2018-11-15       Impact factor: 5.555

9.  Anthropometry, carbohydrate and lipid metabolism in the East Flanders Prospective Twin Survey: heritabilities.

Authors:  N Y Souren; A D C Paulussen; R J F Loos; M Gielen; G Beunen; R Fagard; C Derom; R Vlietinck; M P Zeegers
Journal:  Diabetologia       Date:  2007-08-11       Impact factor: 10.122

  9 in total

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