Literature DB >> 6684425

The role of GTP in prostaglandin E1 stimulation of adenylate cyclase in platelet membranes.

J M Stein, B R Martin.   

Abstract

Adenylate cyclase activity in platelet membrane preparations was measured in the presence of prostaglandin E1 (PGE1), GTP and a non-hydrolysable analogue of GDP, guanosine 5'-[beta-thio]diphosphate (GDP[beta S]). A dose-dependent inhibition of adenylate cyclase by GDP[beta S] was observed that could be reversed either by adding increased amounts of GTP or of PGE1.

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Year:  1983        PMID： 6684425      PMCID： PMC1152231          DOI： 10.1042/bj2140231

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  13 in total

1.  Activation by GTP of liver adenylate cyclase in the presence of high concentrations of ATP.

Authors:  N Kimura; K Nakane; N Nagata
Journal:  Biochem Biophys Res Commun       Date:  1976-06-21       Impact factor: 3.575

2.  Activation of rat liver plasma membrane adenylate cyclase by a cytoplasmic protein factor.

Authors:  C A Doberska; B R Martin
Journal:  FEBS Lett       Date:  1977-10-15       Impact factor: 4.124

3.  Requirement for guanosine triphosphate in the prostaglandin activation of adenylate cyclase of platelet membranes.

Authors:  G Krishna; J P Harwood
Journal:  J Biol Chem       Date:  1972-04-10       Impact factor: 5.157

4.  A highly sensitive adenylate cyclase assay.

Authors:  Y Salomon; C Londos; M Rodbell
Journal:  Anal Biochem       Date:  1974-04       Impact factor: 3.365

Review 5.  Biochemical properties of hormone-sensitive adenylate cyclase.

Authors:  E M Ross; A G Gilman
Journal:  Annu Rev Biochem       Date:  1980       Impact factor: 23.643

6.  Platelet plasma membrane glycoproteins. Evidence for the presence of nonequivalent disulfide bonds using nonreduced-reduced two-dimensional gel electrophoresis.

Authors:  D R Phillips; P P Agin
Journal:  J Biol Chem       Date:  1977-03-25       Impact factor: 5.157

7.  Properties of a factor in cytosol that enhances hormones-stimulated adenylate cyclase activity.

Authors:  A Crawford; S MacNeil; H Amirrasooli; S Tomlinson
Journal:  Biochem J       Date:  1980-05-15       Impact factor: 3.857

8.  Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.

Authors:  F Eckstein; D Cassel; H Levkovitz; M Lowe; Z Selinger
Journal:  J Biol Chem       Date:  1979-10-10       Impact factor: 5.157

9.  Regulation of human platelet adenylate cyclase by epinephrine, prostaglandin E1, and guanine nucleotides. Evidence for separate guanine nucleotide sites mediating stimulation and inhibition.

Authors:  M L Steer; A Wood
Journal:  J Biol Chem       Date:  1979-11-10       Impact factor: 5.157

10.  A simple enzymic method for the synthesis of adenosine 5'-[alpha-32P]triphosphate on a preparative scale.

Authors:  B R Martin; H P Voorheis
Journal:  Biochem J       Date:  1977-03-01       Impact factor: 3.857
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  4 in total

1.  Inhibition of human platelet adenylate cyclase by collagen fibres. Effect of collagen is additive with that of adrenaline, but interactive with that of thrombin.

Authors:  R W Farndale; A B Winkler; B R Martin; M J Barnes
Journal:  Biochem J       Date:  1992-02-15       Impact factor: 3.857

2.  Activation of adenylate cyclase in human platelet membranes by guanosine 5'-[beta gamma-imido]triphosphate is inhibited by cyclic-AMP-dependent phosphorylation. Slow activation occurs in the absence of ATP.

Authors:  R W Farndale; S K Wong; B R Martin
Journal:  Biochem J       Date:  1987-03-15       Impact factor: 3.857

3.  Evidence for regulation of human platelet adenylate cyclase by phosphorylation. Inhibition by ATP and guanosine 5'-[beta-thio]diphosphate occur by distinct mechanisms.

Authors:  I A Wadman; R W Farndale; B R Martin
Journal:  Biochem J       Date:  1991-06-15       Impact factor: 3.857

4.  GTP-independent stimulation of rabbit heart adenylate cyclase by isoproterenol at physiological ATP concentrations.

Authors:  S E Harding; A M Hopwood; P Harris
Journal:  Basic Res Cardiol       Date:  1989 Jan-Feb       Impact factor: 17.165
  4 in total

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