Literature DB >> 667828

Effects of 5-fluorouracil on 5-fluorodeoxyuridine 5'-monophosphate and 2-deoxyuridine 5'-monophosphate pools, and DNA synthesis in solid mouse L1210 and rat Walker 256 tumors.

P Klubes, K Connelly, I Cerna, H G Mandel.   

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Year:  1978        PMID: 667828

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


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  13 in total

1.  Biochemical determinants of tumor sensitivity to 5-fluorouracil: ultrasensitive methods for the determination of 5-fluoro-2'-deoxyuridylate, 2'-deoxyuridylate, and thymidylate synthetase.

Authors:  R G Moran; C P Spears; C Heidelberger
Journal:  Proc Natl Acad Sci U S A       Date:  1979-03       Impact factor: 11.205

Review 2.  Tomudex (ZD1694): from concept to care, a programme in rational drug discovery.

Authors:  A L Jackman; F T Boyle; K R Harrap
Journal:  Invest New Drugs       Date:  1996       Impact factor: 3.850

Review 3.  Cellular pharmacology of fluorinated pyrimidines in vivo in man.

Authors:  J S Kovach; R W Beart
Journal:  Invest New Drugs       Date:  1989-04       Impact factor: 3.850

4.  Effect of concurrent calcium leucovorin infusion on 5-fluorouracil cytotoxicity against murine L1210 leukemia.

Authors:  P Klubes; I Cerna; M A Meldon
Journal:  Cancer Chemother Pharmacol       Date:  1981       Impact factor: 3.333

5.  An optimized synthesis of 18F-labelled 5-fluorouracil and a reevaluation of its use as a prognostic agent.

Authors:  G W Visser; G C Gorree; B J Braakhuis; J D Herscheid
Journal:  Eur J Nucl Med       Date:  1989

6.  5-fluorouracil-methotrexate synergy: enhancement of 5-fluorodeoxyridylate binding to thymidylate synthase by dihydropteroylpolyglutamates.

Authors:  D J Fernandes; J R Bertino
Journal:  Proc Natl Acad Sci U S A       Date:  1980-10       Impact factor: 11.205

7.  Effect of guanosine on antitumor activity of fluorinated pyrimidines against P 388 leukemia.

Authors:  M Iigo; A Hoshi
Journal:  Cancer Chemother Pharmacol       Date:  1984       Impact factor: 3.333

8.  Lack of enhanced cytotoxicity of cultured L1210 cells using folinic acid in combination with sequential methotrexate and fluorouracil.

Authors:  L L Danhauser; R Heimer; E Cadman
Journal:  Cancer Chemother Pharmacol       Date:  1985       Impact factor: 3.333

9.  Enhanced 5-fluorouracil cytotoxicity and elevated 5-fluoronucleotides in the rat Walker carcinosarcoma following methotrexate pre-treatment: a 19F-MRS study in vivo.

Authors:  P M McSheehy; M J Prior; J R Griffiths
Journal:  Br J Cancer       Date:  1992-03       Impact factor: 7.640

10.  The validity of the labelling index in tumour studies.

Authors:  E Hamilton; J Dobbin
Journal:  Br J Cancer       Date:  1985-01       Impact factor: 7.640

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