Literature DB >> 6667703

Evaluation of 99mTc-dichloro bis (1,2-dimethylphosphino) ethane (99mTc-DMPE) for myocardial scintigraphy in man.

R Dudczak, P Angelberger, R Homan, K Kletter, R Schmoliner, H Frischauf.   

Abstract

99mTc-DMPE was used for myocardial scintigraphy in ten patients with coronary artery disease. As in 201T1 studies regional activity of 99mTc-DMPE was reduced in infarcted myocardium. However, activity accumulation of 99mTc-DMPE in the heart was faint, while that in the liver was prominent. The activity ratio of heart to liver improved with time, whereas that of heart to lung decreased. The scintigraphic quality was considerably worse in 99mTc-DMPE studies than in those with 201Tl, due to high background activity. Also the visualization of the ribs and sternum interfered with the interpretation of the scintigrams. From these results it appears that 201Tl remains still the agent of choice for myocardial perfusion scintigraphy.

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Year:  1983        PMID： 6667703     DOI： 10.1007/bf00251611

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  4 in total

1.  Basal kinetic studies of Tc-99m DMPE as a myocardial imaging agent in the dog.

Authors:  H Nishiyama; E Deutsch; R J Adolph; V J Sodd; K Libson; E L Saenger; M C Gerson; M Gabel; S J Lukes; J L Vanderheyden; D L Fortman; K L Scholz; L W Grossman; C C Williams
Journal:  J Nucl Med       Date:  1982-12       Impact factor: 10.057

2.  Effect of coronary blood flow on uptake and washout of Tc-99m DMPE and Tl-201.

Authors:  H Nishiyama; R J Adolph; E Deutsch; V J Sodd; K Libson; M C Gerson; E L Saenger; S J Lukes; M Gabel; J L Vanderheyden; D L Fortman
Journal:  J Nucl Med       Date:  1982-12       Impact factor: 10.057

3.  Cationic Tc-99m complexes as potential myocardial imaging agents.

Authors:  E Deutsch; K A Glavan; V J Sodd; H Nishiyama; D L Ferguson; S J Lukes
Journal:  J Nucl Med       Date:  1981-10       Impact factor: 10.057

4.  Heart imaging with cationic complexes of technetium.

Authors:  E Deutsch; W Bushong; K A Glavan; R C Elder; V J Sodd; K L Scholz; D L Fortman; S J Lukes
Journal:  Science       Date:  1981-10-02       Impact factor: 47.728
  4 in total
  7 in total

1.  The birth of a new radiopharmaceutical. Industrial perspective: from IND to NDA.

Authors:  L P Giering; J E Smith
Journal:  J Nucl Cardiol       Date:  1995 Jan-Feb       Impact factor: 5.952

2.  The utilization of Tc-99m-TBI as a myocardial perfusion agent in exercise studies: comparison with Tl-201 thallous chloride and examination of its biodistribution in humans.

Authors:  S T Sia; B L Holman; K McKusick; P Rigo; F Gillis; V Sporn; N Perez-Balino; A Mitta; H Vosberg; Z Szabo
Journal:  Eur J Nucl Med       Date:  1986

3.  99mTc-sestamibi can improve the inferior attenuation of TL-201 myocardial spect imaging.

Authors:  S J Wang; Y T Chen; C L Hwang; M S Lin; C H Kao; S H Yeh
Journal:  Int J Card Imaging       Date:  1993-06

Review 4.  Myocardial kinetics of radiolabeled perfusion agents: basis for perfusion imaging.

Authors:  S T Dahlberg; J A Leppo
Journal:  J Nucl Cardiol       Date:  1994 Mar-Apr       Impact factor: 5.952

5.  Myocardial perfusion imaging with 99mTc-methoxy-isobutyl-isonitrile (MIBI): comparison of short and long time intervals between rest and stress injections. Preliminary results.

Authors:  R Taillefer; L Laflamme; G Dupras; M Picard; D C Phaneuf; J Léveillé
Journal:  Eur J Nucl Med       Date:  1988

6.  The scintigraphic evaluation of myocardial infarction and regional ventricular performance using technetium-99m hexakis (t-butylisonitrile) technetium (I) (TBI): a new myocardial imaging agent.

Authors:  S Campbell; B L Holman; J M Kirshenbaum; E M Antman; J Lister-James; A Davison; J Kozlowski; R J English; A G Jones
Journal:  Eur J Nucl Med       Date:  1986

7.  Clinical comparison between thallium-201 and Tc-99m-methoxy isobutyl isonitrile (hexamibi) myocardial perfusion imaging for detection of coronary artery disease.

Authors:  R Taillefer; R Lambert; G Dupras; J Grégoire; J Léveillé; R Essiambre; D C Phaneuf
Journal:  Eur J Nucl Med       Date:  1989
  7 in total

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