Literature DB >> 66652

Prenatal diagnosis of neural tube defects. III. A reevaluation of the alpha-fetoprotein assay.

M E Kimball, A Milunsky, E Alpert.   

Abstract

Alpha-fetoprotein was measured in 2209 amniotic fluid samples under improved assay conditions. All cases of open neural tube defects had elevated values greater than 5 SD above the mean. The false positive rate based on the 3 SD cutoff is estimated at less than 9.15%. Alpha-fetoprotein assays are recommended for all patients undergoing second trimester amniocentesis, optimally between 14 and 16 weeks' gestation.

Entities:  

Keywords:  Amniocentesis; Congenital Abnormalities; Diseases; Evaluation; Examinations And Diagnoses; Laboratory Examinations And Diagnoses; Laboratory Procedures; Neonatal Diseases And Abnormalities; Research Methodology; Retrospective Studies; Studies

Mesh：

Substances：

Year:  1977        PMID： 66652

Source DB:  PubMed          Journal:  Obstet Gynecol        ISSN： 0029-7844            Impact factor:   7.661


  8 in total

1.  Anencephaly with placental attachment.

Authors:  C K Sasidharan; P Anoop
Journal:  Indian J Pediatr       Date:  2002-11       Impact factor: 1.967

2.  Maternal serum alpha-fetoprotein screening for neural tube defects. Report of a combined study in Germany and short overview on screening in populations with low birth prevalence of neural tube defects.

Authors:  W Fuhrmann; H K Weitzel
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

3.  Hazards of prenatal detection of neural tube defects.

Authors:  P F Hall
Journal:  Can Med Assoc J       Date:  1979-04-21       Impact factor: 8.262

4.  Hazards of prenatal detection of neural-tube defects by screening maternal serum for alpha-fetoprotein.

Authors:  R G Davidson; L J Sheffield
Journal:  Can Med Assoc J       Date:  1978-05-20       Impact factor: 8.262

5.  Alpha-fetoprotein in antenatal diagnosis of neural tube defects.

Authors:  N Wald; H Cuckle; P E Polani
Journal:  Br Med J       Date:  1978-01-28

6.  Meckel syndrome and the prenatal diagnosis of neural tube defects.

Authors:  M J Seller
Journal:  J Med Genet       Date:  1978-12       Impact factor: 6.318

Review 7.  Genetics of microphthalmos.

Authors:  M Warburg
Journal:  Int Ophthalmol       Date:  1981-08       Impact factor: 2.031

8.  Reactivity of amniotic fluid alpha-fetoprotein with concanavallin A in diagnosis of neural tube defects.

Authors:  C J Smith; P C Kelleher; L Bélanger; L Dallaire
Journal:  Br Med J       Date:  1979-04-07
  8 in total

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