| Literature DB >> 6664751 |
Abstract
Two interactive, computer-controlled tests--critical flicker fusion and discriminant reaction time tasks--are described. These tasks, and subjective sedation ratings using visual analogue scales, were shown to be sensitive in a dose-related fashion to the effects of CNS depressants (diazepam, 15 mg and lorazepam, 1 and 2 mg). Such brief, interactive, computerized tasks should be useful in screening new agents for CNS activity in humans.Entities:
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Year: 1983 PMID： 6664751 DOI： 10.2466/pms.1983.57.3.691
Source DB: PubMed Journal: Percept Mot Skills ISSN： 0031-5125