Literature DB >> 6662549

Intracellular catabolin-like activity in cultured synovial tissue.

J T Dingle, E Qi.   

Abstract

The time course of the synthesis and secretion of catabolin-like activity by porcine synovial tissue was determined. Ex vivo tissue had no demonstrable activity, but short-term culture (less than 1 h) induced cellular accumulation of activity. This accumulation, which preceded secretion, was reversibly inhibited by cycloheximide. The activity was localized in the cystol fraction.

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Year:  1983        PMID： 6662549     DOI： 10.1007/bf02661709

Source DB:  PubMed          Journal:  In Vitro        ISSN： 0073-5655


  17 in total

1.  Human synovium releases a factor which stimulates chondrocyte production of PGE and plasminogen activator.

Authors:  J E Meats; M B McGuire; R G Russell
Journal:  Nature       Date:  1980-08-28       Impact factor: 49.962

2.  Cardiac catabolic factors: the degradation of heart valve intercellular matrix.

Authors:  R S Decker; J T Dingle
Journal:  Science       Date:  1982-02-19       Impact factor: 47.728

3.  A possible role for catabolin in tissue remodelling and repair.

Authors:  J T Dingle
Journal:  Ciba Found Symp       Date:  1981

4.  Human mononuclear cell factors mediate cartilage matrix degradation through chondrocyte activation.

Authors:  H E Jasin; J T Dingle
Journal:  J Clin Invest       Date:  1981-09       Impact factor: 14.808

5.  Characterization of proteins from human synovium and mononuclear leucocytes that induce resorption of cartilage proteoglycan in vitro.

Authors:  J Saklatvala; S J Sarsfield; L M Pilsworth
Journal:  Biochem J       Date:  1983-02-01       Impact factor: 3.857

6.  Macrophage factor that induces neutral protease secretion by normal rabbit chondrocytes. Studies of some properties and effects on metabolism of chondrocytes.

Authors:  K Deshmukh-Phadke; S Nanda; K Lee
Journal:  Eur J Biochem       Date:  1980-02

7.  Effects of antirheumatoid drugs on the production and action of porcine catabolin.

Authors:  H Sheppeard; L M Pilsworth; B Hazleman; J T Dingle
Journal:  Ann Rheum Dis       Date:  1982-10       Impact factor: 19.103

8.  Catabolin--a cartilage catabolic factor from synovium.

Authors:  J T Dingle
Journal:  Clin Orthop Relat Res       Date:  1981-05       Impact factor: 4.176

9.  Characterization of catabolin, the major product of pig synovial tissue that induces resorption of cartilage proteoglycan in vitro.

Authors:  J Saklatvala
Journal:  Biochem J       Date:  1981-12-01       Impact factor: 3.857

10.  A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures.

Authors:  R W Farndale; C A Sayers; A J Barrett
Journal:  Connect Tissue Res       Date:  1982       Impact factor: 3.417
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  3 in total

1.  In vivo studies of articular tissue damage mediated by catabolin/interleukin 1.

Authors:  J T Dingle; D P Page Thomas; B King; D R Bard
Journal:  Ann Rheum Dis       Date:  1987-07       Impact factor: 19.103

Review 2.  What's happened to catabolin?

Authors:  H Sheppeard; K G Couchman
Journal:  Rheumatol Int       Date:  1987       Impact factor: 2.631

3.  Production of cartilage degrading activity by human synovial tissues.

Authors:  M F Brown; B L Hazleman; J T Dingle; D J Dandy; A H Murley
Journal:  Ann Rheum Dis       Date:  1987-04       Impact factor: 19.103
  3 in total

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