| Literature DB >> 6652022 |
Abstract
Our studies of the metastatic behaviour of FSA1231 and FSA1233 show that the role of selection processes of metastatic variants at the secondary sites is minimal in the spontaneous metastasis of these systems. In contrast, tumour-cell release efficiency (number of blood-borne clonogenic tumour-cells) correlates well with the difference in spontaneous lung metastasis efficiencies of the cell clones FSA1231 and FSA1233. Also, the different tumour-cell release efficiencies could explain the discrepancy between artificial and spontaneous metastasis of these cell clones.Entities:
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Year: 1983 PMID: 6652022 PMCID: PMC2011557 DOI: 10.1038/bjc.1983.273
Source DB: PubMed Journal: Br J Cancer ISSN: 0007-0920 Impact factor: 7.640