Literature DB >> 6641911

The effect of jaundiced sera and bile salts on cultured beating rat heart cells.

E Bogin, O Better, I Harari.   

Abstract

Jaundiced serum from common bile duct ligated rats, added to cultured heart cells, decreased the beating rate, caused an early cessation of beating and production of higher levels of lactate in the media. Deoxycholate and cholate are the main bile acids in jaundiced serum; deoxycholate caused similar effects, which suggests that it is the toxic substance responsible for heart function alterations seen in patients with severe jaundice.

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Year:  1983        PMID: 6641911     DOI: 10.1007/BF01990384

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  9 in total

1.  INHIBITORY EFFECTS OF BILE ACIDS ON ADENOSINE TRIPHOSPHATASE, OXYGEN CONSUMPTION, AND THE TRANSPORT AND DIFFUSION OF WATER-SOLUBLE SUBSTANCES IN THE SMALL INTESTINE OF THE RAT.

Authors:  T M PARKINSON; J A OLSON
Journal:  Life Sci (1962)       Date:  1964-02

2.  ENZYMATIC DETERMINATION AND THIN-LAYER CHROMATOGRAPHY OF BILE ACIDS IN BLOOD.

Authors:  T IWATA; K YAMASAKI
Journal:  J Biochem       Date:  1964-11       Impact factor: 3.387

3.  HEMOLYSIS AND AUGMENTATION OF HEMOLYSIS BY NEUTRAL STEROIDS AND BILE ACIDS.

Authors:  G WEISSMANN; H KEISER
Journal:  Biochem Pharmacol       Date:  1965-04       Impact factor: 5.858

4.  STUDIES OF LYSOSOMES. VI. THE EFFECT OF NEUTRAL STEROIDS AND BILE ACIDS ON LYSOSOMES IN VITRO.

Authors:  G WEISSMANN
Journal:  Biochem Pharmacol       Date:  1965-04       Impact factor: 5.858

5.  In vitro studies on single beating rat heart cells. I. Growth and organization.

Authors:  I HARARY; B FARLEY
Journal:  Exp Cell Res       Date:  1963-02       Impact factor: 3.905

6.  The isolation and cultivation of rat heart cells.

Authors:  I Harary; F Hoover; B Farley
Journal:  Methods Enzymol       Date:  1974       Impact factor: 1.600

7.  Impaired skeletal muscle vasomotor response to infused noradrenaline in baboons with obstructive jaundice.

Authors:  L Bomzon; P B Wilton; T A McCalden
Journal:  Clin Sci Mol Med       Date:  1978-07

8.  Impaired cardiovascular responsiveness in liver disease.

Authors:  M R Lunzer; S P Newman; A G Bernard; K K Manghani; S P Sherlock; J Ginsburg
Journal:  Lancet       Date:  1975-08-30       Impact factor: 79.321

9.  Cholic acid and the heart: in vitro studies of the effect on heart rate and myocardial contractility in the rat.

Authors:  P Joubert
Journal:  Clin Exp Pharmacol Physiol       Date:  1978 Jan-Feb       Impact factor: 2.557

  9 in total
  10 in total

1.  QT interval prolongation in end-stage liver disease cannot be explained by nonhepatic factors.

Authors:  Divyang Patel; Prabhpreet Singh; William Katz; Christopher Hughes; Kapil Chopra; Jan Němec
Journal:  Ann Noninvasive Electrocardiol       Date:  2014-04-24       Impact factor: 1.468

Review 2.  Bile acids regulate cardiovascular function.

Authors:  Sandeep Khurana; Jean-Pierre Raufman; Thomas L Pallone
Journal:  Clin Transl Sci       Date:  2011-06       Impact factor: 4.689

3.  Effect of bile acid on electrophysiological properties of rabbit sino-atrial node in vitro.

Authors:  H Kotake; T Itoh; M Watanabe; I Hisatome; J Hasegawa; H Mashiba
Journal:  Br J Pharmacol       Date:  1989-10       Impact factor: 8.739

4.  Cardiomyopathy reverses with recovery of liver injury, cholestasis and cholanemia in mouse model of biliary fibrosis.

Authors:  Moreshwar S Desai; Zeena Eblimit; Sundararajah Thevananther; Astrid Kosters; David D Moore; Daniel J Penny; Saul J Karpen
Journal:  Liver Int       Date:  2014-01-12       Impact factor: 5.828

5.  Bile acids increase intracellular Ca(2+) concentration and nitric oxide production in vascular endothelial cells.

Authors:  T Nakajima; Y Okuda; K Chisaki; W S Shin; K Iwasawa; T Morita; A Matsumoto; J I Suzuki; S Suzuki; N Yamada; T Toyo-Oka; R Nagai; M Omata
Journal:  Br J Pharmacol       Date:  2000-08       Impact factor: 8.739

6.  Bile salt-induced intracellular Ca++ accumulation in type II pneumocytes.

Authors:  D G Oelberg; S A Downey; M M Flynn
Journal:  Lung       Date:  1990       Impact factor: 2.584

7.  Effects of bile acids on ventricular muscle contraction and electrophysiological properties: studies in rat papillary muscle and isolated ventricular myocytes.

Authors:  O Binah; I Rubinstein; A Bomzon; O S Better
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-02       Impact factor: 3.000

8.  Thermodynamic interference with bile acid demicelleization reduces systemic entry and injury during cholestasis.

Authors:  Cristiane de Oliveira; Biswajit Khatua; Bara El-Kurdi; Krutika Patel; Vivek Mishra; Sarah Navina; Bradley J Grim; Srishti Gupta; Marek Belohlavek; Brian Cherry; Jeffery Yarger; Matthew D Green; Vijay P Singh
Journal:  Sci Rep       Date:  2020-05-21       Impact factor: 4.379

Review 9.  What Every Intensivist should Know about Impairment of Cardiac Function and Arrhythmias in Liver Disease Patients: A Review.

Authors:  Sanjeev Arya; Prashant Kumar; Bhuwan Tiwari; Shantanu Belwal; Sanjay Saxena; Haider Abbas
Journal:  Indian J Crit Care Med       Date:  2020-12

10.  Gut microbiota in sarcopenia and heart failure.

Authors:  Chia-Feng Liu; W H Wilson Tang
Journal:  J Cardiovasc Aging       Date:  2022-07-05
  10 in total

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