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Literature DB >> 6639004

Comparative analysis of conjugative plasmids mediating gentamicin resistance in Staphylococcus aureus.

Abstract

Five gentamicin-resistant clinical isolates of Staphylococcus aureus were found to contain self-transmissible plasmids of 32 to 37 megadaltons in size. Restriction endonuclease digests of the plasmids were markedly similar to those of reference plasmids of unrelated geographical origin, thus suggesting the significant contribution of common conjugal plasmids to the emergence of gentamicin resistance in S. aureus populations.

Entities: Chemical Species

Mesh：

Substances：
Gentamicins

Year: 1983 PMID： 6639004 PMCID： PMC185346 DOI： 10.1128/AAC.24.3.450

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

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